[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100371709":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":61,"collaborators":25,"id":63,"slug":25,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":25,"enrollmentInfo":72,"targetDuration":25,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":44,"whyStopped":25,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University Hospital, Lille","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with haemorrhagic disease","EXPERIMENTAL","Patients with von Willebrand disease or Patients with Glanzmann Thrombasthenia",[13,14],"Device: Sublingual videomicroscopy","Biological: blood sample",{"label":16,"type":6,"description":17,"interventionNames":18},"Control group","Patients with moderate or severe hemophilia A or women carrying the hemophilia gene",[13],[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Sublingual videomicroscopy","Measurement of sublingual capillary density by video microscopy",[16,9],null,{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":25},"BIOLOGICAL","blood sample","Collection of citrate tubes of 5 mL at baseline and at 36 months",[9],[32],{"name":33,"affiliation":5,"role":34},"Antoine Rauch, MD,PhD","PRINCIPAL_INVESTIGATOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":39,"email":40},"CONTACT","3 20445962 (poste 29673)","+33","antoine.rauch@chru-lille.fr",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"CHU de Lille","RECRUITING","Lille","Nord","59000","France","FR",{"type":51,"coordinates":52},"Point",[53,54],3.05512,50.63391,{"lat":54,"lon":53},[57,59],{"name":58,"role":37,"phone":25,"phoneExt":25,"email":25},"Antoine Rauch, MD",{"name":60,"role":34,"phone":25,"phoneExt":25,"email":25},"Antoine Rauch, md",{"type":62,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100371709",false,"NCT04119908","Videomicroscopy for the Prediction of Bleeding in Constitutional Haemorrhagic Diseases","Interest of Sublingual Videomicroscopy for the Prediction of Bleeding in Von Willebrand Disease and Other Constitutional Haemorrhagic Diseases","VIDEO-BLEED","Inclusion Criteria:\n\n* Adult patient with a significant form of von Willebrand disease (according to the inclusion criteria of the Willebrand Disease French Reference Center), a Glanzmann Thrombasthenia, a moderate to severe Haemophilia A or a woman carrying the hemophilia gene\n* Social insured patient\n\nExclusion Criteria:\n\n* Minor patient\n* Refusal of consent\n* Person benefiting from a system of legal protection\n* Pregnant patient","ALL","18 Years",{"count":73,"type":74},400,"ESTIMATED","INTERVENTIONAL",[77],"NA","In Willebrand disease, there is currently no test available to identify non-invasively patients with a high risk of bleeding from angiodysplasias The study propose to use a sublingual capillary bed analysis by video-microscopy, a sensitive, reproducible and non-invasive technique, to assess whether sublingual capillary density is predictive of hemorrhagic risk for patients with von Willebrand disease.",[80,81],"Von Willebrand Diseases","Glanzmann Thrombasthenia",[83,84,85,86],"constitutional haemorrhagic diseases, Videomicroscopy, prediction, bleeding","Videomicroscopy","prediction","bleeding","2026-05-19",{"date":89,"type":90},"2026-05-20","ACTUAL",{"date":92,"type":90},"2023-05-24",{"date":94,"type":74},"2028-05-24",{"name":5,"class":6},1]