Virtual Reality and Dual-Task Training for Cortical Plasticity in Children With Brachial Plexus Injury

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age7-14
SponsorIstanbul Aydın University

About this trial

Brachial plexus birth injury (BPBI) is a condition that occurs when the nerves controlling the arm are injured during birth, leading to weakness, limited movement, and sensory problems. These motor difficulties may also affect cognitive processes related to movement. BPBI requires long-term follow-up and rehabilitation.

This study will compare two treatment approaches in children with BPBI:

* virtual reality (VR)-based exercises, and * motor-cognitive dual-task exercises. We will examine their effects on brain adaptation (cortical activation), muscle strength, joint motion, proprioception, and upper-limb function. Fourteen children aged 7-14 years will be randomly assigned to one of the two programs, each delivered for 12 weeks. Afterward, participants will continue a 9-month home program. Assessments will be conducted at baseline, after treatment, and at 12 months, including functional MRI (fMRI).

This study will be the first to evaluate long-term brain changes and functional outcomes after these two rehabilitation approaches in children with BPBI.

Eligibility criteria

Qualifiers

Children aged 7-14 years

Diagnosed with unilateral DBPP

C5-C6 or C5-C7 involvement (Narakas I, IIa, IIb)

Modified Pediatric Mini-Mental Scale score ≥26

Disqualifiers

Previous nerve surgery for DBPP

Surgery within the past year or Botulinum Toxin injection within the past 3 months

Any neurological condition other than DBPP

Vision or hearing impairments affecting participation

Trial design

Treatments tested in this trial

  • Conventional Physiotherapy Program
  • Virtual Reality
  • Dual Task

Treatment groups

14 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Istanbul Aydın University

Lead sponsor

Istanbul University

Collaborator

Biruni University

Collaborator