[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100535160":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":73,"collaborators":26,"id":75,"slug":26,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":26,"eligibilityCriteria":80,"healthyVolunteers":76,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":26,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":26,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"University of Maryland, Baltimore","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Virtual reality arm","EXPERIMENTAL","In the virtual reality intervention, participants will complete the scheduled educational module five times in the week of the intervention. This VR is assisting users in using immersive reality to reduce pain, learning cognitive and behavior self-coping skills and retraining the pain pathways. There are several sessions, which will be delivered using an all-in-one head-mounted display. Each session varies in duration approximately from 3 to 15 minutes.",[13],"Device: Relievrx",{"label":15,"type":16,"description":17,"interventionNames":18},"Audio Mp4 arm","PLACEBO_COMPARATOR","In the audio intervention, participants will complete the scheduled module 5 times a week of the intervention. The content is similar to that of the VR, which will be delivered by the audio player. Each session varies in duration approximately from 3 to 15 minutes.",[19],"Other: Audio Mp4",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Relievrx","The RelieVRx program is a prescription-use immersive virtual reality system intended to provide adjunctive treatment based on cognitive behavioral therapy skills and other evidence-based behavioral methods for patients (age 18 and older) with a diagnosis of chronic lower back pain (defined as moderate to severe pain lasting longer than three months). The device is intended for in-home use for the reduction of pain and pain interference associated with chronic lower back pain.",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Audio Mp4","Audio Mp4 modules ranging from 3-15 minutes with guided meditation.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Katia Matychak, MS","CONTACT","410-706-5975","katiamatychak@umaryland.edu",[38,62],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Luana Colloca","RECRUITING","Baltimore","Maryland","21201-1512","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-76.61219,39.29038,{"lat":50,"lon":49},[53,57,60],{"name":54,"role":34,"phone":55,"phoneExt":26,"email":56},"Luana Colloca, MD,PhD,MS","301-364-8089","Colloca@umaryland.edu",{"name":58,"role":59,"phone":26,"phoneExt":26,"email":26},"Kendyl Carlisle, MD","SUB_INVESTIGATOR",{"name":61,"role":59,"phone":26,"phoneExt":26,"email":26},"Julia Terhune, MD",{"facility":63,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":64,"geoPoint":66,"contacts":67},"University of Maryland",{"type":47,"coordinates":65},[49,50],{"lat":50,"lon":49},[68,71],{"name":69,"role":34,"phone":55,"phoneExt":26,"email":70},"Luana Colloca, MD, PhD, MS","colloca@umaryland.edu",{"name":33,"role":34,"phone":72,"phoneExt":26,"email":36},"4107065975",{"type":74,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100535160",false,"NCT06248216","Virtual Reality Therapy for Cancer-Treatment Associated Symptoms","Implementation of an At-Home Multimodal Integrative Therapy Via Virtual Reality for Patients With Cancer-Treatment Associated Symptoms","Inclusion Criteria:\n\n* Adults ages 18-88\n* Cancer diagnosis (histology verified)\n* Had surgical intervention, completed chemotherapy or radiation for therapeutic purposes\n\n  -\\>3 months since last cancer treatment, but participants currently undergoing endocrine or immunotherapy treatments are permissible\n* Documented symptoms of cancer or cancer therapy including at least one of the following: pain, anxiety, sleep difficulty, fatigue, neuropathy\n* English speaker (written and spoken)\n\nExclusion Criteria:\n\n* Severe psychiatric condition (e.g. schizophrenia, bipolar disorders, autism) leading to hospitalization within the last 3 years\n* Any personal (or family first degree) history of mania, schizophrenia, or other psychoses\n* Diagnosis and treatment of chronic pain, neuropathy, fatigue, sleep or anxiety disorder prior to cancer diagnosis\n* Current Hospice or palliative care only recipients\n* Color-blindness\n* Impaired or uncorrected hearing\n* Lifetime alcohol\u002Fdrug dependence or alcohol\u002Fdrug abuse in past 3 months\n* Conditions that would interfere with the VR mask placement (e.g. trauma, burn, infection)\n* Known history of severe motion sickness\n* Pregnancy or breast feeding","ALL","18 Years","88 Years",{"count":85,"type":86},30,"ESTIMATED","INTERVENTIONAL",[89],"NA","We propose an innovative approach to symptom management in cancer patients following cancer treatments, utilizing a Multimodal Integrative Therapy (MIT) delivered via Virtual Reality (VR) program, authorized by the US Food and Drug Administration for in-home use. Our primary goal is to generate pilot data on the effects of MIT-VR program on pain, fatigue, sleep, depression, and anxiety in participants suffering from chronic cancer symptoms following cancer treatments.",[92,93,94],"Cancer","Cancer Pain","Virtual Reality","2026-04-27",{"date":97,"type":98},"2026-04-29","ACTUAL",{"date":100,"type":98},"2024-12-04",{"date":102,"type":86},"2027-12",{"name":5,"class":6},2]