Weaning Ventilator Using Heart, Lung And Diaphragm Ultrasound
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHanoi Medical University
About this trial
Postextubation distress is detrimental to the prognosis of critically ill patients with successful spontaneous breathing trial. Failure to wean is known to be connected with heart, lung, and diaphragm problems. The aim of this study was to investigate how a composite model comprising diaphragm, lung, and heart ultrasonography indications could predict the weaning outcome.
Methods: Ultrasonic features of the diaphragm, heart, and lungs are going to be collected along with clinical data about the patients. Either the successful weaning group or the failed weaning group is going to comprised the patients. Multivariate logistic regression analysis is going to be used to identify the variables that may be associated with the likelihood of weaning failure. A multiindicator combination model is going to be developed to increase the predictive accuracy after the possible indicators' accuracy in foretelling the weaning outcome was assessed.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age >= 18
The duration of postoperative mechanical ventilation >= 48 hours
Disqualifiers
Patient had a diagnosis of progressive neuromuscular diseases
Patient had a history of cardiovascular or respiratory disease who depend on a ventilator at home (COPD, severe bronchial asthma)
Patients had thoracic surgery or mitral valve surgery.
Trial population
All patients with a duration of mechanical ventilation through an endotracheal tube of more than 48 hours and meeting the criteria of readiness to wean off mechanical ventilation will be included in the study.
Trial design
Design model
Ecologic or community
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
190 Participants
are grouped into 1 trial groupGroup A: The ventilator weaning patients
Trial outcomes
Primary outcomes
1
The ventilator weaning outcome
The outcome of weaning ventilation process (successful or failure)
Time frame
after 48 hours of extubationSecondary outcomes
1
The hospital length of stay
The time between hospital admission and discharge
Time frame
Approximately 5-15 days postextubation2
The ICU length of stay
The time between ICU admission and discharge
Time frame
Approximately 2-15 days postextubation3
The duration of mechanical ventilation
The time from the start of mechanical ventilation to extubation
Time frame
Daily assessment of requirement of mechanical ventilation from the time of intubation until the date of weaning mechanical ventilation, up to 12 monthsSponsors and contacts
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Source ClinicalTrials.gov