[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572617":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":38,"responsibleParty":65,"collaborators":25,"id":68,"slug":25,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":25,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":25,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":101,"overallStatus":40,"whyStopped":25,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":120},{"fullName":5,"class":6},"Georgia State University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Wild Blueberry","EXPERIMENTAL","22 g of freeze-dried wild blueberry freeze-dried powder per day",[13],"Dietary Supplement: Wild Blueberry",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","22 g of freeze-dried macronutrient-matched placebo powder per day",[19],"Dietary Supplement: Placebo",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Daily consumption of 22 g of freeze-dried wild blueberry freeze-dried powder for 8 weeks",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Daily consumption of 22 g of freeze-dried macronutrient-matched placebo powder for 8 weeks",[15],[30],{"name":31,"affiliation":5,"role":32},"Rafaela G Feresin, PhD","PRINCIPAL_INVESTIGATOR",[34],{"name":31,"role":35,"phone":36,"phoneExt":25,"email":37},"CONTACT","404-413-1233","berries@gsu.edu",[39],{"facility":5,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Atlanta","Georgia","30303","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-84.38798,33.749,{"lat":50,"lon":49},[53,55,56,59,61,63],{"name":54,"role":35,"phone":36,"phoneExt":25,"email":37},"Rafaela Feresin, PhD",{"name":31,"role":32,"phone":25,"phoneExt":25,"email":25},{"name":57,"role":58,"phone":25,"phoneExt":25,"email":25},"Andrew Gerwitz, PhD","SUB_INVESTIGATOR",{"name":60,"role":58,"phone":25,"phoneExt":25,"email":25},"Tricia Z King, PhD",{"name":62,"role":58,"phone":25,"phoneExt":25,"email":25},"Brett J Wong, PhD",{"name":64,"role":58,"phone":25,"phoneExt":25,"email":25},"Elizabeth L Tighe, PhD",{"type":32,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Rafaela G. Feresin","Associate Professor","100572617",false,"NCT06735599","Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure","Effects of Wild Blueberry Consumption on Gut, Brain, and Cardiovascular Health in Non-Hispanic Black and White Adults With High Blood Pressure","Inclusion Criteria:\n\n* Individuals 45-65 years of age\n* Diagnosis of elevated blood pressure or stage 1 hypertension (systolic blood pressure = 120-139 mmHg and\u002For diastolic blood pressure = 80-89 mmHg) for at least 6 months\n* BMI 25-35 kg\u002Fm2 via anthropometric measurements.\n* Ability to give consent\n\nExclusion Criteria:\n\n* Allergies to berries\n* Use of one hypertensive drug for less than three months\n* Use of more than one anti-hypertensive or statin drug, insulin, antibiotics, and anti-inflammatory drugs, active cancer, gastrointestinal, renal, cardiovascular, thyroid, and neurological disorders or severe head injury\n* Smoking\n* Alcohol consumption (\\>2 drinks\u002Fday)\n* Consuming antioxidant, probiotic, and prebiotic supplements\n* Pregnant or lactating\n* Participating in a weight loss program","ALL","45 Years","65 Years",{"count":78,"type":79},40,"ESTIMATED","INTERVENTIONAL",[82],"NA","The purpose of the study is to determine the effectiveness of wild blueberries on cardiovascular health, cognitive function, and gut microbiota composition in non-Hispanic Black and White adults with elevated blood pressure.",[85,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100],"Hypertension (Without Type 2 Diabetes Mellitus)","High Blood Pressure","Male","Female","Adult","Cognition","Endothelial Function (Reactive Hyperemia)","Oxidative Stress","Diet","Overweight","Body Composition Measurement","Gut Microbiome","Arterial Stiffness","Caucasian Whites","Inflammation","Microvascular Function",[102,103,94,86,104,105,106,107,108,109,110],"Blueberries","Hypertension","Endothelial Function","Cognitive Function","Dietary intervention","functional foods","gut microbiota","arterial stiffness","microvascular function","2026-03-23",{"date":113,"type":114},"2026-03-27","ACTUAL",{"date":116,"type":114},"2024-09-17",{"date":118,"type":79},"2027-01-01",{"name":5,"class":6},1]