[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100534478":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":21,"centralContacts":30,"locations":36,"responsibleParty":56,"collaborators":60,"id":64,"slug":21,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":21,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":39,"whyStopped":21,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Medical University of South Carolina","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Nicotine treatment","All participants recieve active nicotine treatment for 12 weeks.",[12,13,14],"Behavioral: Counseling","Behavioral: Contingency management","Behavioral: Text-based support",[16,22,26],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"BEHAVIORAL","Counseling","Research staff will provide skills-based counseling at remote weekly visits, starting at Day 0. Counseling sessions will be brief (\\~5-10 minutes) and will focus on strategies for preparing for the quit attempt, dealing with triggers, refusal skills, and enhancing motivation.",[9],null,{"type":17,"name":23,"description":24,"armGroupLabels":25,"otherNames":21},"Contingency management","Contingency management (CM): CM will be provided to all study participants to promote abstinence from all nicotine products. Incentives for abstinence (based on submission of a negative cotinine sample) will be provided on an escalating schedule during treatment (Days 8-84).",[9],{"type":17,"name":27,"description":28,"armGroupLabels":29,"otherNames":21},"Text-based support","All participants will be provided with evidence-based nicotine cessation resources. For those who are vaping nicotine, participants will be provided information for This is Quitting (SMS text-based program). For those who are primarily smoking cigarettes, NCI's QuitSTART (mobile app, web content), as well SmokefreeTXT (SMS-text based program), will be recommended, potentially in addition to This is Quitting for those using multiple products. These resources provide real time monitoring of nicotine use, mood, triggers and lapses.",[9],[31],{"name":32,"role":33,"phone":34,"phoneExt":21,"email":35},"Elizabeth Chapman","CONTACT","864.898.2992","chapmanb@musc.edu",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Medical University of South Carolina - Charleston","RECRUITING","Charleston","South Carolina","29403","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-79.93275,32.77632,{"lat":49,"lon":48},[52],{"name":53,"role":33,"phone":54,"phoneExt":21,"email":55},"Ela Williams","843-792-4097","williela@musc.edu",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"PRINCIPAL_INVESTIGATOR","Erin McClure","Associate Professor - Faculty",[61],{"name":62,"class":63},"National Cancer Institute (NCI)","NIH","100534478",false,"NCT06239350","Young Adult Tobacco\u002FNicotine and Cannabis Co-use","The Impact of Cannabis and Tobacco\u002FNicotine Product Co-use in Young Adults: Prospective Cessation Evaluation and Substitution","YouthCAT","Inclusion Criteria:\n\n* Between the ages of 18 and 25 years old\n* Must use at least one nicotine or tobacco product (nicotine vaping and\u002For cigarettes) on at least 20 out of the past 30 days for at least the past 3 months\n* Must express interest in nicotine cessation (all products)\n* Must submit a positive instant-read, oral fluid cotinine sample prior to enrollment\n* Must report use of cannabis on at least 10 out of the past 30 days\n* Must submit a positive instant-read cannabinoid test prior to enrollment\n* Must be able to provide informed consent\n\nExclusion Criteria:\n\n* Any significant or acutely unstable medical, psychiatric, or substance use problem that would contraindicate research, interfere with safety, compromise data integrity, or preclude consistent study participation\n* Pregnant (self-report) or trying to become pregnant\n* Self-reported use of medications with smoking cessation efficacy\n* Immediate interest in cannabis cessation or treatment",true,"ALL","18 Years","25 Years",{"count":76,"type":77},350,"ESTIMATED","INTERVENTIONAL",[80],"NA","The goal of this project is to better understand the relationship between tobacco\u002Fnicotine and cannabis using behavioral economics during a tobacco\u002Fnicotine quit attempt. All participants will receive tobacco\u002Fnicotine cessation treatment (smoking and\u002For vaping treatment) for 12 weeks. To qualify, participants must be between the ages of 18-25 and use tobacco products (smoke cigarettes and\u002For vape nicotine) and use cannabis (in any form). Participants do not need to be interested in quitting cannabis\u002Fmarijuana to qualify. This study is being conducted by the Medical University of South Carolina. All procedures are conducted remotely and there is no in-person visits are needed.",[83,84],"Tobacco Use Disorder","Nicotine Dependence",[86,87,88,89],"tobacco","vaping","cessation","cannabis\u002Fmarijuana","2026-06-10",{"date":92,"type":93},"2026-06-12","ACTUAL",{"date":95,"type":93},"2024-05-13",{"date":97,"type":77},"2028-01-03",{"name":5,"class":6},1]