[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Amy Colwell\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":39},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":4,"enrollmentInfo":16,"targetDuration":4,"studyType":19,"phases":20,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":5},"100609044",false,"NCT07209436","Impact of Pectoral Versus Paravertebral Blocks on Pain and Physical Well-Being in Implant-Based Breast Reconstruction","Inclusion Criteria:\n\n* Adult patient 18 years or older\n* Scheduled for unilateral or bilateral immediate implant-based breast reconstruction\n* Therapeutic or prophylactic indication\n* Patient understands the study procedures and objectives and is willing to participate\n* Patient willing to and capable of providing informed consent\n\nExclusion Criteria:\n\n* Delayed breast reconstruction\n* Allergy or contraindication to local anesthetics (PVB or PECS blocks)\n* History of radiation therapy\n* Planned sedation or general anesthesia protocol variation\n* Morbid obesity as defined as a BMI greater than 40 kg\u002Fm2\n* Renal insufficiency\n* Chronic pain syndrome or central sensitization disorders (e.g., fibromyalgia, CRPS)\n* Use of implanted pain devices or neuromodulators\n* Pre-existing neurological deficits in the surgical field\n* Current chronic opioid use (daily use within the 2 weeks before surgery and duration of use greater than 4 weeks)\n* Use of any nerve medications in the past 6 months, including antiepileptic medications (gabapentin, carbamazepine)\n* History of drug or alcohol abuse or habitual alcohol intake greater than two standard drinks per day (e.g., two beers, two glasses of wine, or two mixed drinks)\n* Any comorbidity that results in moderate or severe functional limitation, inability to communicate with the investigators or hospital staff\n* History of a psychiatric disorder which would interfere with the study procedure\n* Incarceration\n* Any issue that at the discretion of the investigator would contraindicate the subject's participation\n* Inability to understand the procedures and objectives of the study\n* Inability to or unwilling to provide informed consent","ALL","18 Years",{"count":17,"type":18},212,"ESTIMATED","INTERVENTIONAL",[21],"NA","The broad aim of this study is to compare the effectiveness of paravertebral and pectoral blocks on pain and physical well-being of patients undergoing immediate implant-based breast reconstruction.",[24],"Breast Reconstruction",[24,26],"Breast cancer","RECRUITING","2026-01-20",{"date":30,"type":31},"2026-01-22","ACTUAL",{"date":33,"type":31},"2025-11-19",{"date":35,"type":18},"2028-06",{"name":37,"class":38},"Amy Colwell","OTHER",""]