[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Andrei Iagaru\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":40},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100507775",false,"NCT05891769","99mTc Sestamibi SPECT\u002FCT vs 18F Fluorocholine PET\u002FCT","Evaluation of Patients With Suspected Parathyroid Adenoma and Negative or Equivocal 99mTc Sestamibi SPECT\u002FCT Using 18F Fluorocholine PET\u002FCT","18FCH","Inclusion Criteria:\n\n1. Suspected parathyroid adenoma (elevated serum calcium and inappropriately normal or high levels of parathyroid hormone)\n2. Negative or equivocal 99mTc Sestamibi SPECT\u002FCT\n3. Able to provide written consent\n4. Total bilirubin ≤ 1.5 x upper limit of normal (ULN)\n5. Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) ≤ 5 xULN\n6. Karnofsky performance status of \\>50 (or ECOG\u002FWHO equivalent)\n7. Women must not be pregnant per the Department of Radiology Policy on Imaging in Potentially Pregnant and Pregnant Women.\n\nExclusion Criteria:\n\n1. Less than 18 years old at the time of radiotracer administration\n2. Creatinine clearance (calculated using Cockcroft-Gault formula, or measured) \\\u003C 60 mL\u002Fmin or serum creatinine \\>1.5 x ULN\n3. QTcF \\>470 msec on electrocardiogram (ECG) or congenital long QT syndrome","ALL","18 Years",{"count":19,"type":20},100,"ESTIMATED","INTERVENTIONAL",[23,24],"PHASE2","PHASE3","This study proposes the use of a well-established PET isotope, Fluorine-18 (18F), bound to Choline, for a prospective single-center, single-arm study for participants with suspected parathyroid adenoma and negative or equivocal standard of care 99mTc Sestamibi SPECT\u002FCT",[27],"Parathyroid Adenoma","RECRUITING","2026-06-19",{"date":31,"type":32},"2026-06-24","ACTUAL",{"date":34,"type":32},"2023-09-27",{"date":36,"type":20},"2028-07-01",{"name":38,"class":39},"Andrei Iagaru","OTHER",""]