[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Avicenna Military Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100600345",false,"NCT07096284","The PvCO2-PaCO2\u002FCaO2-CvO2 Ratio in Septic Shock","Prognostic Value and Kinetics of the PvCO2-PaCO2\u002FCaO2-CvO2 Ratio Compared to Arterial Lactate in the Initial Phase of Septic Shock","SepsisO2CO2R","Inclusion Criteria:\n\nPatients aged over 18 years presenting with septic shock, defined as sepsis with persistent hypotension requiring vasopressors to maintain a mean arterial pressure (MAP) ≥ 65 mmHg and lactatemia \\> 2 mmol\u002FL despite adequate fluid resuscitation. Sepsis is defined by the presence of a suspected or confirmed infectious source associated with organ dysfunction (neurological, respiratory, renal, hepatic, or hematological). \\[Sepsis 3 criteria\\]\n\nExclusion Criteria:\n\n* Absence of central venous access.\n* Central venous access not positioned in the superior vena cava (e.g., femoral access).","ALL","18 Years",{"count":19,"type":20},30,"ESTIMATED","OBSERVATIONAL","The ratio of the venous-arterial carbon dioxide partial pressure difference to the arteriovenous oxygen content difference (Pv-aCO₂\u002FCa-vO₂) may be a marker of anaerobic metabolism in patients with acute circulatory failure. This study aims to assess the prognostic value of the PvCO2-PaCO2\u002FCaO2-CvO2 in the early phase of septic shock.",[24],"Septic Shock",[26,27],"sepsis","anaerobic metabolism","RECRUITING","2026-03-28",{"date":31,"type":32},"2026-03-31","ACTUAL",{"date":34,"type":32},"2025-01-05",{"date":36,"type":20},"2026-06-30",{"name":38,"class":39},"Avicenna Military Hospital","OTHER",3,""]