[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Baris Gencer\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":40},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100509991",false,"NCT05920629","Moderate Alcohol Consumption and Heart Function in Patients With a Recent Myocardial Infarction","Moderate Alcohol Consumption and Heart Function in Patients With a Recent Myocardial Infarction: a Multicentre Randomized Controlled Trial","Moderate","Inclusion Criteria:\n\n* Hospitalization for acute ST-elevation MI (STEMI) or non ST-elevation MI (NSTEMI) within 365 days prior to screening\n* Men and women aged ≥18 years who are capable and willing to provide consent\n* ECG ischemic changes, such as persistent or dynamic ST-segment deviation\n* Evidence of positive high-sensitive troponin\n* Confirmation of coronary heart disease aetiology by angiography\n* Capacity to complete study visits with strict adherence to the protocol assignment\n* Self-reported average alcohol consumption of between 1 and 28 standard units per week in the 12 months prior to the index hospitalization.\n\nExclusion Criteria:\n\n* High alcohol consumption, defined as an average of \\>28 alcoholic standard units\u002Fweek in the 12 months prior to the index hospitalization\n* Alcohol use disorder (AUDIT score \\>20 at screening)\n* History of alcohol or substance abuse\n* Naïve to alcohol consumption\n* Light alcohol consumption (\\\u003C1 standard units by week)\n* Prior severe heart failure (NYHA III-IV)\n* Severe LV dysfunction at screening (\\\u003C30%)\n* History of gastric ulcer or gastro-intestinal bleeding\n* Serious chronic liver disease or liver test elevation (\\> 3 times upper limit normal range)\n* Personal history of any colon or liver cancer\n* Any active malignancy (less than 5 years or ongoing treatment)\n* Estimated glomerular filtration rate 15 ml\u002Fmin\u002F1.73m² or end-stage renal disease\n* Any medication (investigator's discretion) making study participation impractical or precluding required follow-up\n* History of organ transplant\n* Participation in another trial testing intervention on similar CV outcomes (investigator's discretion)\n* Any medical, geographic, or social factor making study participation impractical or precluding required follow-up.\n* Pregnant, breastfeeding or planning to become pregnant within 12 months.","ALL","18 Years",{"count":19,"type":20},220,"ESTIMATED","INTERVENTIONAL",[23],"NA","A total of 220 patients (110 per arm) who report moderate alcohol consumption between 1 and 28 standard units (1 standard unit = \\~10 grams) per week in the 12 months prior to hospital admission will be planned for randomization, using a 1:1 ratio to pursue moderate alcohol consumption (1 standard unit per day for women and 2 standard units per day for men) or abstinence (except for one drink on predefined\u002Fagreed special occasions) for a total duration of 3 months. An echocardiography will be performed at baseline and 3 months to assess changes in systolic cardiac function (LVEF) for the primary endpoint. A core laboratory team blinded to assignment will perform data interpretation.",[26],"Myocardial Infarction","RECRUITING","2026-04-22",{"date":30,"type":31},"2026-04-28","ACTUAL",{"date":33,"type":31},"2023-06-01",{"date":35,"type":20},"2026-04-30",{"name":37,"class":38},"Baris Gencer","OTHER",4,""]