[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Barry Sandler\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":48},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":13,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100536354",false,"NCT06263738","Cold and Heat Investigation to Lower Levels of Depression","CHILL'D","Inclusion Criteria:\n\n* Individuals who currently meet study criteria for depression or individuals who do not currently meet criteria for depression\n* English or Spanish speaking (able to provide informed consent and complete questionnaires in one of these languages)\n* Able and willing to adhere to trial requirements, including attending all trial visits, preparatory and follow-up sessions, and completing all trial evaluations.\n\nExclusion Criteria:\n\n* Previous adverse reaction to hypothermia, hyperthermia and\u002For infrared exposure\n* Use of any medication that may impact thermoregulatory capacity.\n* Pregnancy, active lactation, or intention to become pregnant during the study period.\n* Endorses current active suicidal ideation with a plan or made a suicide attempt in the prior 6 months.",true,"ALL","18 Years","65 Years",{"count":20,"type":21},162,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study will recruit 112 medically healthy adults (aged 18-65) currently experiencing depressive symptoms to be randomized to receive either a single Whole Body Hyperthermia (heat therapy) treatment or a Whole Body Hyperthermia treatment followed by a cold water plunge. Participants will complete a baseline assessment of their depressive symptoms as well as 1-week and 2-week post-treatment followup assessments.",[27,28,29],"Depression","Mood Disorders","Healthy (Controls)",[27,28,31,32,33,34,35],"Mental Health","Integrative Health","Hyperthermia","Sauna","Cold Plunge","RECRUITING","2025-11-11",{"date":39,"type":40},"2025-11-13","ACTUAL",{"date":42,"type":40},"2024-05-14",{"date":44,"type":21},"2027-04-01",{"name":46,"class":47},"Barry Sandler","OTHER",""]