[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Botanee Group Co., Ltd.\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100584636",false,"NCT06891924","A Clinical Study on Pre-operative Intervention With Products During Aesthetic Medicine","Clinical Study on Pre-operative Intervention With Products to Mitigate Skin Discomfort During Aesthetic Medicine","Inclusion Criteria:\n\n* health females aged 35-60;\n* subjects with rough dark, loose fine lines;\n* no history of cosmetic allergies;\n* subjects are willing to use the test serum on split-face for 28 days;\n* subjects are willing to suffer the Fotona 4D treatment (Frac3 and Piano modes) on the face;\n* subjects are willing to use the basic skincare products for 28 days, and acceptable for split-face use of the test products or the control product for 14 days;\n* written informed consent and portrait right consent were obtained from all participants before study entry.\n\nExclusion Criteria:\n\n* anyone who is pregnant, nursing an infant, or planning a pregnancy during the study;\n* subjects with known allergies or sensitivities to the ingredients in any of the study products;\n* any symptoms of facial flushing, erythema, papules, desquamation, or edema as evaluated by a physician prior to initial screening or Fotona4D Pro treatment;\n* unhealed skin lesions;\n* participated in any other clinical trial within one month;\n* received facial skin treatments including but not limited to lasers, chemical peels, and dermal fillers within one month;\n* taken\u002Finjected anti-allergy medication in the past one month;\n* participants in other clinical trials at the same time;\n* any subjects that the investigator considers ineligible.",true,"FEMALE","35 Years","60 Years",{"count":20,"type":21},33,"ESTIMATED","INTERVENTIONAL",[24],"NA","This clinical trial aims to evaluate whether a 14-day pre-operative application of the test product (containing MLYAAT-1002®, a proprietary anti-aging complex) can mitigate skin discomfort during Fotona 4D laser therapy (Frac3 and Piano modes) by comparing clinical evaluation, skin attributes measurement and subject self-assessment.",[27,28,29],"Skin Aging","Skin Condition","Skin Manifestations","NOT_YET_RECRUITING","2025-03-26",{"date":33,"type":34},"2025-04-01","ACTUAL",{"date":36,"type":21},"2025-03-25",{"date":38,"type":21},"2025-06-01",{"name":40,"class":41},"Botanee Group Co., Ltd.","INDUSTRY",""]