[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Cappagh National Orthopaedic Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100630580",false,"NCT07489521","Arthrosamid vs. Steroid for the Management of Knee Osteoarthritis","A Randomised Control Trial of the Use of an Intraarticular Hydrogel Arthrosamid® vs. Steroid for the Non-operative Management of Knee Osteoarthritis","Inclusion Criteria:\n\n* Adults\n* Symptomatic single side knee pain.\n* Patients with diagnosis of knee osteoarthritis radiographic Kellgren and Lawrence system OA grade II-III-IV on x ray or MRI.\n\nExclusion Criteria:\n\n* Inflammatory conditions,\n* Cancer,\n* acute infection,\n* pregnancy and breastfeeding.\n* Uncontrolled diabetes mellitus,\n* Joint diseases in the knee, such as rheumatoid arthritis or gout, history of knee surgery with metallic implant.\n* If patient has undergone knee arthroscopy in past 6 months.\n* Intra-articular injection of corticosteroids during the previous 3 months, intra-articular injection of other drugs, such as hyaluronic acid over the previous 1 year.\n* Contraindications for intra-articular injection, such as thrombocytopenia, coagulopathy, articular infection of knee, impairment of immunity.",true,"ALL","18 Years","100 Years",{"count":20,"type":21},200,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","This study will be a randomised control trial of the use of intra-articular Arthrosamid® a novel intraarticular hydrogel vs. standard of care (steroid and local anaesthetic) for the non-operative management of knee osteoarthritis.",[27,28,29],"Osteo Arthritis Knee","Osteoarthritis","Intraarticular Injection",[28,31,32],"knee","steroid injection","RECRUITING","2026-04-23",{"date":36,"type":37},"2026-04-28","ACTUAL",{"date":39,"type":37},"2026-01-29",{"date":41,"type":21},"2027-09",{"name":43,"class":44},"Cappagh National Orthopaedic Hospital","OTHER",""]