[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Cyprus Institute of Neurology and Genetics\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":13,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100500658",false,"NCT05799118","Study of the Role of Genetic Modifiers in Hemoglobinopathies","INHERENT","Inclusion Criteria:\n\n* Clinical diagnosis of an inherited hemoglobinopathy, including sickle cell disease (SCD), β-thalassemia, and α-thalassemia; all genotypes will be considered.\n* Age ≥ 2 years old at the time of the collection of the phenotypic data.\n* There will be no limits on study participants in terms of gender, ethnicity, morbidities.\n\nExclusion Criteria:\n\n* Patients treated with stem cell transplantation or genetic therapy.\n* Age \\\u003C 2 years old at the time of the collection of the phenotypic data.\n* Patient or legal representative for minors unwilling or unable to give consent.","ALL","2 Years",{"count":18,"type":19},30000,"ESTIMATED","OBSERVATIONAL","This study will investigate the role of genetic modifiers in hemoglobinopathies through a large-scale, multi-ethnic genome-wide association study (GWAS).",[23,24,25,26],"Sickle Cell Disease","Thalassemia, Beta","Thalassemia Alpha","Hemoglobinopathies",[28,29,30,31],"GWAS","thalassemia","sickle cell disease","genetic modifiers","RECRUITING","2024-03-19",{"date":35,"type":36},"2024-03-20","ACTUAL",{"date":38,"type":36},"2022-10-01",{"date":40,"type":19},"2027-09-30",{"name":42,"class":43},"Cyprus Institute of Neurology and Genetics","OTHER",26,""]