[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Department of Cardiology German Heart Center Munich TUM University Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100634744",false,"NCT07543666","The ISAR InflEx Trial (Inflammation and Exercise)","Impact of Different Exercise Intensities and Durations on Systemic Inflammation - The ISAR InflEx Trial (Inflammation and Exercise) -","InflEx","Inclusion Criteria:\n\n* BMI 25.0 - 30.0 kg\u002Fm²\n* age 18 - 45 years\n* informed consent\n* no regular physical activity (≤1x\u002Fweek of structured exercise)\n* willingness to strictly follow and adhere to the intervention protocol for the entire study\n\nExclusion Criteria:\n\n* any acute or chronic illness\n* pregnancy and breastfeeding\n* active smoking\n* Regular use of medication","ALL","18 Years","45 Years",{"count":20,"type":21},33,"ESTIMATED","INTERVENTIONAL",[24],"NA","A sedentary lifestyle and obesity are associated with chronic low-grade inflammation and an elevated risk of cardiovascular disease (CVD). This study aims to systematically characterize and compare the effects of three distinct exercise modalities - moderate-intensity, vigorous-intensity, and short-duration maximal exercise - each differing in duration and intensity, on systemic inflammation and immune function. The study investigates the potential of exercise as an effective anti-inflammatory intervention for the prevention of CVD.",[27,28],"Inflammation","Obesity (Disorder)",[30,31,32,33],"exercise","inflammation","obesity","physical activity","RECRUITING","2026-04-21",{"date":37,"type":38},"2026-04-24","ACTUAL",{"date":40,"type":38},"2026-01-01",{"date":42,"type":21},"2027-06",{"name":44,"class":45},"Department of Cardiology German Heart Center Munich TUM University Hospital","OTHER",""]