[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"EXACT Therapeutics AS\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":51},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100581462",false,"NCT06850623","Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer","A Phase 2 Study to Investigate the Efficacy and Safety of Acoustic Cluster Therapy With Modified FOLFIRINOX in Patients With Locally Advanced Pancreatic Cancer","ENACT","Inclusion Criteria:\n\n* Not deemed suitable for primary curative surgery and have radiographic and pathological disease consistent with inoperable LAPC or borderline resectable pancreatic cancer.\n* Suitable to receive treatment with mFOLFIRINOX according to the Investigator's assessment.\n\nExclusion Criteria:\n\n• Any prior anti-cancer treatment for pancreatic cancer (e.g. chemotherapy, surgery, radiation). Palliative bypass procedure and bile duct stenting are allowed.","ALL","18 Years",{"count":19,"type":20},25,"ESTIMATED","INTERVENTIONAL",[23],"PHASE2","The purpose of the study is to assess the efficacy and safety of Acoustic Cluster Therapy (ACT) when given in addition to chemotherapy for treatment of Locally Advanced Pancreatic Cancer.",[26],"Locally Advanced Pancreatic Adenocarcinoma",[28,29,30,31,32,33,34,35,36,37],"pancreatic cancer","PS101","ultrasound","microbubbles","Pancreatic Ductal Carcinoma","locally advanced pancreatic cancer","first line treatment","chemotherapy","Acoustic Cluster Therapy","mFOLFIRINOX","RECRUITING","2026-03-30",{"date":41,"type":42},"2026-04-03","ACTUAL",{"date":44,"type":42},"2025-06-19",{"date":46,"type":20},"2027-07-15",{"name":48,"class":49},"EXACT Therapeutics AS","INDUSTRY",10,""]