[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Friedrich-Alexander-Universität Erlangen-Nürnberg\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":97},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,77],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":20,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100618546",false,"NCT07333027","Lonely in Depression","Effects of Loneliness in the Treatment of Depression","Inclusion Criteria:\n\n* primary diagnosis of depression according to ICD-10 (F32 or F33), as diagnosed by a physician or clinical psychologist in conjunction with the M.I.N.I. Mini-International Neuropsychiatric Interview diagnostic tools\n* inpatient elective or emergency admission to one of the two psychiatric clinics; - age over 18 years\n* sufficient understanding of spoken and written German\n* informed voluntary consent\n\nExclusion Criteria:\n\n* a current lack of capacity to provide consent (e.g., pronounced psychotic symptoms, stuporous depressive syndrome, and thought constriction to suicidality)\n* previous participation in the study\n* pregnancy or breastfeeding\n* inpatient stay of less than 7 days, even if the patients initially met the inclusion criteria.","ALL","18 Years",{"count":18,"type":19},200,"ESTIMATED","3 Months","OBSERVATIONAL","The goal of this prospective study is to better understand the link between loneliness and depression in the inpatient psychiatric treatment of depression. It aims to answer:\n\nDo lonely and not lonely persons benefit the same way from inpatient depression treatment? Is loneliness a clinical relevant factor in inpatient treatment of depression? What are the underlying biopsychosocial mechanisms?\n\nParticipants will be asked to do some\n\n* self-report questionnaires\n* clinical interview\n* biosampling (blood, saliva, stool) at three main measurement timepoints (1. begin of inpatient treatment, 2. day of discharge, 3. three months after discharge).",[24,25],"Depression Disorder","Loneliness",[27,28,29,30,31],"loneliness","depression","prospective","biosampling","clinical","RECRUITING","2026-06-11",{"date":35,"type":36},"2026-06-15","ACTUAL",{"date":38,"type":36},"2026-02-05",{"date":40,"type":19},"2027-09",{"name":42,"class":43},"Friedrich-Alexander-Universität Erlangen-Nürnberg","OTHER",2,{"id":46,"slug":4,"hasResults":10,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":10,"sex":15,"minAge":52,"maxAge":16,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},"100632917","NCT07519915","Improvement of Understanding of Pediatric Sacral Neuromodulation: Therapeutic Strategies and Outcome Variables","Stimulation Modeling and Adaptive Response Tracking in Pediatric Gastrointestinal Motility Disorders","SMART-GUT","Inclusion Criteria:\n\n* informed consent of patient and care taker\n* gastrointestinal motility disorder, disregarding underlying diseases\n* exclusion of mechanical obstructions in the gastrointestinal passage\n* age between 3 and 18\n\nExclusion Criteria:\n\n* pregnancy\u002Fbreast feeding\n* decreased renal or thyroidal function\n* drug intake of Beta-blockers, antispasmodics, cyclopropane, bisulfite compounds, haloperidol, heroin, meperidine, metamizole, methadone, morphine, nitrofurantoin, opium alkaloids, phenobarbital, phenylbutazone, probenecid, rifamycin\n* contradictions for MRI\n* indication for analgosedation for MRI\n* inflammatory bowel diseases\n* fractures\u002Fdifferent anatomy in sacral region\n* epilepsy\n* presence of cardiac pacemakers","3 Years",{"count":54,"type":19},25,"INTERVENTIONAL",[57],"NA","The goal of this study is to learn about the effects of sacral neuromodulation in pediatric patients with gastrointestinal motility disorders. By combining advanced neuroimaging, patient-specific biophysical modeling, electrophysiological characterization, and clinical translation, the SMART-GUT project establishes a comprehensive framework to systematically investigate neuromodulation in this pediatric population. This integrative approach enables a direct link between mechanism, targeting, and clinical outcome.",[60,61,62],"Gastrointestinal Motility Disorders in Children","Hirschsprung Disease","Constipation - Functional",[64,65,66,67],"pediatric gastrointestinal motility disorders","chronic constipation","Hirschsprung disease","sacral neuromodulation","2026-04-06",{"date":70,"type":36},"2026-04-09",{"date":72,"type":36},"2018-07-01",{"date":74,"type":19},"2029-12-31",{"name":42,"class":43},1,{"id":78,"slug":4,"hasResults":10,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":10,"sex":15,"minAge":4,"maxAge":16,"enrollmentInfo":83,"targetDuration":4,"studyType":55,"phases":85,"briefSummary":86,"conditions":87,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":76},"100490475","NCT05666609","Fistula-in-ano in Infants and Children","Fistula-in-ano in Infants and Children: Prospective, Randomized Clinical Trail on the Duration of Non-cutting Seton Placement","Inclusion Criteria:\n\n* any patient with FIA and treatment with non-cutting seton placement in our institution\n* regardless of underlying diagnoses\n* age 0-18 years\n\nExclusion Criteria:\n\n* none",{"count":84,"type":19},20,[57],"In this prospective, randomized trail, duration of non-cutting seton placement in patients with fistula-in-ano is evaluated.",[88],"Fistula in Ano","2025-08-31",{"date":91,"type":36},"2025-09-08",{"date":93,"type":36},"2023-01-01",{"date":95,"type":19},"2027-12-31",{"name":42,"class":43},""]