[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Hesham Nabil Ali Al-Qamhawy\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":48},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100628822",false,"NCT07466641","LLLLT vs Piezocision in Accelerating Orthodontic Canine Retraction","Effectiveness of Piezocision Versus Low-level Laser Therapy During Orthodontic Canine Retraction: A Comparative Controlled Clinical Study","Inclusion Criteria:\n\n* Age range 18-25 years.\n* Patients with crowding or protrusion requiring at least bilateral maxillary first premolar extraction followed by symmetrical canine retraction.\n* Full set of permanent dentition (third molar not considered).\n* Patients with good oral hygiene.\n\nExclusion Criteria:\n\n* Previous orthodontic treatment.\n* Patients taking medications or suffering from systemic conditions that can affect orthodontic tooth movement.\n* Active periodontal diseases and\u002For untreated carious lesions.\n* Congenital orofacial deformities.\n\nDiscontinuation criteria:\n\n* Multiple missing appointments.\n* Poor oral hygiene.\n* Multiple broken appliances to the extent that interferes with obtaining the treatment objectives.","ALL","18 Years","25 Years",{"count":19,"type":20},21,"ESTIMATED","INTERVENTIONAL",[23],"NA","This comparative controlled clinical study aims to evaluate and compare the effectiveness of piezocision and low-level laser therapy (LLLT) as adjunctive interventions to accelerate orthodontic canine retraction. Participants will be randomly assigned to one of three groups: piezocision, LLLT, or a control group (no adjunctive procedure). The study will assess the impact of these interventions on the rate of tooth movement, the type of tooth movement, and patient experience.",[26,27,28],"Malocclusion, Angle Class II, Division 1","Bimaxillary Protrusion","Class I Malocclusion",[30,31,32,33,34,35],"canine retraction","Low-level laser therapy","laser","piezocision","piezosurgery","orthodontic canine retraction","RECRUITING","2026-05-06",{"date":39,"type":40},"2026-05-11","ACTUAL",{"date":42,"type":40},"2026-04-01",{"date":44,"type":20},"2027-06",{"name":46,"class":47},"Hesham Nabil Ali Al-Qamhawy","OTHER",""]