[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Hospital General de Agudos J. M. Penna\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100624839",false,"NCT07414849","The AMPER Study: Evaluation of the Efficacy of Human Amniotic Membrane Grafting in Preventing Mesh Exposure in Vaginal Reconstructive Surgery Using Polypropylene Mesh.","The Amper Study: Amniotic Membrane for the Prevention of Mesh Exposure in Vaginal Reconstructive Surgery","AMPER","Inclusion Criteria:\n\n* Pelvic organ prolapse (POP) stage II C or greater, defined as C ≥ +1, in women without prior hysterectomy and\u002For with a diagnosis of stress urinary incontinence seeking surgical treatment.\n* Ability to understand study information and provide written informed consent.\n* Availability for follow-up for a minimum of 12 months.\n\nExclusion Criteria:\n\n* Previous surgery with synthetic mesh (via vaginal or abdominal approach) for POP repair.\n* Known adverse reaction to synthetic meshes.\n* Unresolved or active chronic pelvic pain.\n* History of prior abdominal or pelvic radiation.\n* Contraindication to the planned surgical procedure.\n* Current pregnancy.","FEMALE",{"count":18,"type":19},330,"ESTIMATED","INTERVENTIONAL",[22],"NA","This study evaluates the efficacy of adding a human amniotic membrane graft to polypropylene mesh surgery for pelvic prolapse and stress urinary incontinence. The goal is to assess improvements in tissue integration and the reduction of surgical complications",[25,26],"Pelvic Organ Prolapse Vaginal Surgery","Stress Urinary Incontinence in Women",[28,29],"amniotic membrane graft","polypropylene mesh","RECRUITING","2026-06-15",{"date":33,"type":34},"2026-06-17","ACTUAL",{"date":36,"type":34},"2026-03-01",{"date":38,"type":19},"2028-12-31",{"name":40,"class":41},"Hospital General de Agudos J. M. Penna","OTHER",""]