[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Hospital Nord\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":25,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100608521",false,"NCT07202637","Evaluation of the Variation of the Sub-pulmonary Velocity-time Integral to Predict Fluid Responsiveness","Evaluation of the Variation of the Sub-pulmonary Velocity-time Integral to Predict Fluid Responsiveness Prospective Observational Study","Inclusion Criteria:\n\n* Patient with measurable sub-pulmonary VTI in at least one of the two windows: parasternal short-axis or subcostal.\n* Patient with measurable sub-aortic VTI in apical 4-chamber view before and after PLR maneuver.\n* Patient with suspected hypovolemia or whose hemodynamic status justifies vasopressor infusion.\n\nExclusion Criteria:\n\n* Severe left ventricular dysfunction defined by left ventricular ejection fraction (LVEF) \\\u003C 30%.\n* Severe right ventricular dysfunction defined by TAPSE \\\u003C 12 mm.\n* Cardiac arrhythmia or atrial fibrillation.\n* Abdominal compartment syndrome.\n* Amputation of one or both lower limbs.\n* Intracranial hypertension.\n* Pregnant women (ruled out by systematic pregnancy test at ICU admission).\n* Minors.","ALL","18 Years",{"count":18,"type":19},205,"ESTIMATED","OBSERVATIONAL","Fluid administration is the first-line treatment in hypovolemic states in critically ill patients. Prediction of fluid responsiveness is possible with echocardiography by assessing the variation of the sub-aortic velocity-time integral (AoVTI) during a passive leg raising test (PLR) or Mini-fluid challenge. However, VTI-Ao measurement is not feasible in all patients due to poor echogenicity. Validation of new fluid-responsiveness indices may facilitate the evaluation in this patient population. Among the available indices, variation of the sub-pulmonary VTI is a potential criterion.",[23,24],"Fluid Resuscitation","Fluid Responsiveness Predictability",[26,27,28,29],"fluid responsiveness","echocardiography","Passive Leg Raising","Mini Fluid Challenge","RECRUITING","2025-09-23",{"date":33,"type":34},"2025-10-02","ACTUAL",{"date":36,"type":34},"2024-11-07",{"date":38,"type":19},"2027-05",{"name":40,"class":41},"Hospital Nord","OTHER",2,""]