[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Hospital Universitario La Fe\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":67},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100543263",false,"NCT06353594","Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With STEMI","Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With St-segment Elevation Myocardial Infarction (Copernican)","COPERNICAN","Inclusion Criteria:\n\n\\- Patients presenting with STEMI and indication to undergo pPCI.\n\nExclusion Criteria:\n\n* Life expectancy \\\u003C1 year due 1 to non-cardiac disease.\n* Inability to provide informed consent.\n* Cardiogenic shock.\n* Left ventricular ejection fraction \\\u003C15%.\n* Left main disease.\n* Stent thrombosis\n* Patients with prior bypass graft lesions requiring PCI (culprit or non culprit lesions).\n* Patients with chronic total occlusions.\n* Untreatable coronary disease.\n* Non-identified culprit lesion.\n* Known allergy to aspirin, ticagrelor, prasugrel, clopidogrel, paclitaxel or sirolimus.","ALL","18 Years",{"count":19,"type":20},1272,"ESTIMATED","INTERVENTIONAL",[23],"NA","The objective is to compare a reduced stent strategy based on drug-coated balloon (DCB) percutaneous coronary intervention (PCI) with conventional drug-eluting stent (DES) coronary revascularization in patients presenting with ST-segment myocardial infarction (STEMI).\n\nRandomization will be performed after successful culprit-lesion guidewire crossing and flow restoration. Random allocation in a 1:1 fashion to one of the following strategies:\n\n* Study group: reduced stent PCI strategy (DCB-based)\n* Control group: conventional PCI strategy (DES-based).",[26],"ST Elevation Myocardial Infarction",[28],"STEMI","RECRUITING","2026-05-25",{"date":32,"type":33},"2026-05-28","ACTUAL",{"date":35,"type":33},"2024-03-11",{"date":37,"type":20},"2035-09",{"name":39,"class":40},"Hospital Universitario La Fe","OTHER",23,{"id":43,"slug":4,"hasResults":10,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":48,"enrollmentInfo":49,"targetDuration":51,"studyType":52,"phases":4,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":66},"100409823","NCT04616495","Liver Transplantation in Patients With Unresectable Colorectal Liver Metastases","TRASMETIR","Inclusion Criteria:\n\n* ≥ 18 and ≤ years\n* Good performance status, ECOG 0 or 1\n* Resected adenocarcinoma in colon or rectum (R0 resection)\n* Unresectable liver metastases\n* No extrahepatic disease\n* Normal blood tests\n* Response to ≤ 2 lines of chemotherapy (RECIST criteria)\n* ≥ 1 year period since diagnosis of colorectal cancer to enrolment in liver transplant waiting list\n* Signed informed consent\n\nExclusion Criteria:\n\n* Body mass index ≥ 30\n* Positive HIV or HCV\n* Pregnancy at the time of inclusion\n* BRAF mutated status\n* Deterioration of general condition (10% weight loss in the prior 6 months)\n* Other malignancy with disease free survival \\\u003C 5 years\n* Concomitant or prior extrahepatic metastases (histologically or radiologically proved), even if surgically resected.\n* Palliative resection of primary colorectal adenocarcinoma\n* Liver metastases size \\> 5 cm (in the last imaging technique)\n* CEA \\> 80 ng\u002Fml (at time of enrolment in waiting list)\n* No neoadjuvant chemotherapy treatment\n* General contraindication to liver transplantation","65 Years",{"count":50,"type":20},30,"5 Years","OBSERVATIONAL","Multicentric prospective and observational study to assess the 5-year overall survival in a cohort of patients with unresectable liver-only colorectal metastases, well controlled by chemotherapy prior to liver transplantation.",[55,56,57],"Colorectal Cancer","Metastatic Liver Cancer","Liver Metastases","2023-09-21",{"date":60,"type":33},"2023-09-22",{"date":62,"type":33},"2021-09-01",{"date":64,"type":20},"2028-09",{"name":39,"class":40},1,""]