[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Izgi Miray Demirbag\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100605535",false,"NCT07163780","The Effect of the HEP Approach in Infants With Down Syndrome","The Effectiveness of the HEP (Homeostasis-Enrichment-Plasticity) Approach in Infants With Down Syndrome","HEP-DS","Inclusion Criteria:\n\n* Must be between 4 and 12 months old\n* Must have been diagnosed with Down Syndrome\n* Must not be at any neurological risk\n* Parent must agree to participate regularly in the study process\n\nExclusion Criteria:\n\n* History of intraventricular hemorrhage (Grade III or IV)\n* Major vision or hearing impairment\n* History of febrile convulsion\n* Medical conditions (e.g., oxygen dependence) that prevent active participation in the study\n* Participation in other experimental rehabilitation studies","ALL","4 Months","12 Months",{"count":20,"type":21},26,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study evaluates the effect of the HEP (Homeostasis-Enrichment-Plasticity) approach on motor and sensory development in infants with Down syndrome. Thirty-two infants will receive either HEP or traditional therapy over 12 sessions, and outcomes will be measured using standardized developmental tests.",[27],"Down Syndrome (DS)",[29,30,31,32,33],"Down Syndrome","Infants","Early Intervention","Neuroplasticity","Environmental Enrichment","RECRUITING","2025-11-13",{"date":37,"type":38},"2025-11-14","ACTUAL",{"date":40,"type":38},"2025-09-03",{"date":42,"type":21},"2025-12-03",{"name":44,"class":45},"Izgi Miray Demirbag","OTHER",""]