[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"John M. Buatti\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":38},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":5},"100627353",false,"NCT07447531","T2 Star Magnetic Resonance Imaging and Biomarker Blood Testing to Predict the Change and Progress of Malignant Gliomas","Evaluating Iron-Dependent Biomarkers of Malignant Glioma (WHO Grade IV) Progression","Inclusion Criteria:\n\n* Age \\> 21 years\n* New pathologically confirmed diagnosis of WHO grade IV malignant glioma\n* KPS \\> 60\n* Ability to give informed consent for standard of care chemotherapy and radiation therapy on the MR Linac and to study procedures for the protocol\n\nExclusion Criteria:\n\n* History of previous malignancy other than non-melanoma skin cancer in the previous 5 years\n* History of iron metabolic disorder such as hemochromatosis\n* Inability to undergo MR studies due to size, claustrophobia, or metal implants or devices","ALL","21 Years",{"count":18,"type":19},15,"ESTIMATED","INTERVENTIONAL",[22],"NA","This clinical trial studies whether T2 star (T2\\*) magnetic resonance imaging (MRI) and biomarker blood testing can help predict how World Health Organization (WHO) grade IV gliomas (malignant gliomas) might change or progress over time.",[25],"Malignant Glioma","RECRUITING","2026-02-25",{"date":29,"type":30},"2026-03-03","ACTUAL",{"date":32,"type":30},"2025-10-03",{"date":34,"type":19},"2028-10-06",{"name":36,"class":37},"John M. Buatti","OTHER",""]