[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"KBC Split\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":14,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100593565",false,"NCT07008092","Prostaglandin-E Urinary Metabolite (PGE-M) as a Predictor of Acute Appendicitis in Children","Inclusion Criteria:\n\n* children of age 5 -17 years with acute abdominal pain\n* children with clinical signs of acute appendicitis\n\nExclusion Criteria:\n\n* previous diagnosis of chronic and\u002For malignant disease\n* children who had previous abdominal surgery\n* pregnancy",true,"ALL","5 Years","17 Years",{"count":19,"type":20},100,"ESTIMATED","OBSERVATIONAL","Diagnosing acute appendicitis in children remains a clinical challenge, with delayed or incorrect diagnosis potentially leading to serious complications or unnecessary surgery. Prostaglandin E urinary metabolites (PGE-M) have been found elevated in various inflammatory conditions, but their diagnostic value in pediatric appendicitis is not well established. This study aims to assess the potential of PGE-M as a biomarker for acute appendicitis in children.\n\nThe study will be conducted over 12 months and will include 100 children aged 5 to 17 years presenting with acute abdominal pain. In addition to routine laboratory tests, urinary PGE-M levels will be analyzed. The study involves minimal risk to participants",[24,25,26],"Acute Appendicitis","Acute Appendicitis With Rupture","Abdominal Pain (AP)",[28,29,30],"Acute appendicitis","PGE-M","Prostaglandin-E urinary metabolite","RECRUITING","2025-05-29",{"date":34,"type":35},"2025-06-06","ACTUAL",{"date":37,"type":20},"2025-06-02",{"date":39,"type":20},"2026-05-01",{"name":41,"class":42},"KBC Split","OTHER",""]