[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Konya Meram State Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":64},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":16,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100638839",false,"NCT07580144","Effect of Sarcopenia and Frailty on Rocuronium Pharmacodynamics in Geriatric Patients","Inclusion Criteria:\n\n* Scheduled to undergo elective surgery under general anesthesia requiring endotracheal intubation\n* Planned use of rocuronium for neuromuscular blockade\n* Quantitative neuromuscular monitoring planned during anesthesia\n* American Society of Anesthesiologists physical status I-III\n* Ability to provide written informed consent\n* Completion of preoperative frailty and sarcopenia assessment\n\nExclusion Criteria:\n\n* Emergency surgery\n* Known neuromuscular disease\n* History of allergy or contraindication to rocuronium, sugammadex\n* Severe hepatic insufficiency\n* Severe renal insufficiency\n* Use of drugs known to significantly affect neuromuscular transmission\n* Preoperative mechanical ventilation or intensive care unit admission\n* Inability to perform a frailty or sarcopenia assessment\n* Patients in whom quantitative neuromuscular monitoring cannot be properly performed\n* Refusal to participate in the study","ALL","65 Years","80 Years",{"count":18,"type":19},100,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to evaluate whether sarcopenia and frailty affect the pharmacodynamic profile of rocuronium in geriatric patients undergoing elective surgery under general anesthesia.",[23,24,25,26,27],"Sarcopenia","Frailty","Neuromuscular Blockade","Rocuronium","Pharmacodynamics","RECRUITING","2026-05-13",{"date":31,"type":32},"2026-05-15","ACTUAL",{"date":29,"type":32},{"date":35,"type":19},"2026-08-05",{"name":37,"class":38},"Konya Meram State Hospital","OTHER",1,{"id":41,"slug":4,"hasResults":10,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":10,"sex":14,"minAge":46,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":49,"phases":50,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":61,"leadSponsor":63,"locationsCount":39},"100628186","NCT07458360","FRONT Block for Quality of Recovery After Total Hip Arthroplasty","Effect of Femoral Rami and Obturator Nerve Trunk (FRONT) Block on Postoperative Quality of Recovery After Total Hip Arthroplasty: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Scheduled for total hip arthroplasty under spinal anesthesia\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Ability to understand and complete the QoR-15 questionnaire\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Contraindication to spinal anesthesia or regional block\n* Allergy to study medications\n* Chronic opioid use (daily use for more than 3 months)\n* Neurological or neuromuscular disorders affecting the lower extremities\n* Infection at the injection site\n* Coagulation disorders\n* Cognitive impairment prevents questionnaire completion","18 Years",{"count":48,"type":19},80,"INTERVENTIONAL",[51],"NA","This prospective randomized controlled trial evaluates the effect of ultrasound-guided unilateral Femoral Rami and Obturator Nerve Trunk (FRONT) block on postoperative quality of recovery in patients undergoing elective total hip arthroplasty.",[54,55,56],"Osteoarthritis of the Hip","Postoperative Pain","Quality of Recovery","2026-04-25",{"date":59,"type":32},"2026-04-28",{"date":57,"type":32},{"date":62,"type":19},"2026-07-05",{"name":37,"class":38},""]