[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Lindsay Maguire, MD\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100522693",false,"NCT06085937","Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department","Feasibility and Safety of Single Dose Ketamine for Acutely Suicidal Patients in the Emergency Department","Inclusion Criteria:\n\n* Acutely Suicidality (\"yes\" answer to any of items 4 or 5 on C-SSRS \"Suicidal Ideation\" category)\n* Require inpatient stabilization for SI or actions based on clinical observation and interview\n* Are accepted for psychiatric stabilization at the University of Kansas Medical Center's Strawberry Hill campus\n* Have a Glasgow Coma Score (GCS) of 15\n* Age 18-65\n\nExclusion Criteria:\n\n* Current or past history of psychosis\n* Current or recent (past 4 weeks) symptoms of mania\u002Fhypomania as defined by Young Mania Rating Scale (YRMS) score of 12 or greater\n* History of ketamine use disorder\n* History of liver transplant\n* Pregnancy or breastfeeding\n* Imprisonment or inability to consent\n* Positive urine drug screen or serum alcohol level\n* Hypertension (SBP \\> 160 or DBP \\> 100 before administration of ketamine)\n* Hypotension (SBP \\\u003C 90)\n* Presence of acute medical condition requiring admission to medical service\n* Allergy, intolerance, or previous adverse reaction to ketamine\n* Patient has 8+ lifetime ketamine exposures\n* The treating physician determines that the patient is not a good candidate for the study (e.g. medical condition\u002Fprocedure, medication that would contradindicate ketamine treatment)","ALL","18 Years","65 Years",{"count":19,"type":20},50,"ESTIMATED","INTERVENTIONAL",[23],"PHASE1","There is currently no readily available pharmacologic intervention for suicidal ideation, a true psychiatric emergency, in the Emergency Department (ED). Investigators aim to trial low-dose, intravenous ketamine, a drug with well-established use in treatment-resistant depression, for patients who present to the ED with suicidal ideation.",[26,27,28],"Suicide","Suicidal Ideation","Depression","RECRUITING","2026-04-12",{"date":32,"type":33},"2026-04-15","ACTUAL",{"date":35,"type":33},"2024-05-01",{"date":37,"type":20},"2027-04",{"name":39,"class":40},"Lindsay Maguire, MD","OTHER",2,""]