[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Los Angeles General Medical Center\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":39},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":4},"100553784",false,"NCT06490588","Use of Sevoflurane to Test Concept of Cognitive Reserve","The Use of Sevoflurane to Test the Concept of Intra-individual Variability in Bispectral Index Monitor and Cognitive Reserve by Examining Time to Emergence and Recovery","Inclusion Criteria:\n\n* \\- Minimal completion of high-school education\n* Adult patient \\\u003C 85 years of age\n* No prior known history of cognitive\u002Fbrain disease\n* ASA class I-II\n* Undergoing general anesthesia with sevoflurane for maintenance anesthesia\n* Same-day surgery\n* Elective procedures\n* No prior history of cardiac disease\n\nExclusion Criteria:\n\n* \\- History of chronic pain\n* Perioperative use of anesthetic agents other than propofol, fentanyl, dilaudid, and sevoflurane\n* History of alcohol\u002Fsubstance druge abuse\n* Psychiatric history\n* Morbid history\n* History of OSA, stroke, or TIA\n* Blindness\n* Deafness",true,"ALL","18 Years","90 Years",{"count":20,"type":21},70,"ESTIMATED","OBSERVATIONAL","Previous pilot study had demonstrated a correlation between cognitive reserve and BIS variability during steady state of anesthesia. This study, we intend to evaluate the association between BIS variability and emergence and recovery time from anesthesia.",[25,26],"Cognitive Reserve","BIS","NOT_YET_RECRUITING","2024-06-28",{"date":30,"type":31},"2024-07-08","ACTUAL",{"date":33,"type":21},"2024-09",{"date":35,"type":21},"2026-09",{"name":37,"class":38},"Los Angeles General Medical Center","OTHER",""]