[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Maria Elizabeth Rossi da Silva\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":48},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":16,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100589794",false,"NCT06959043","Therapeutic Strategies for Type 2 Diabetes Based on Lifestyle Changes: Plant-based Diet and Physical Exercise","Inclusion Criteria:\n\n* Have a medical diagnosis of type 2 diabetes for a maximum of 5 years.\n* Be omnivorous; Have a Body Mass Index (BMI) ≥ 25 kg\u002Fm2 and \\\u003C 40 kg\u002Fm2;\n* Be between the ages of 45 and 70, both genders.\n* Women should be in the postmenopausal stage;\n* Use no more than three hypoglycemic medications in total;\n* Have the availability for a four-week consecutive hospitalization at CSVN.\n\nExclusion Criteria:\n\n* Be using insulin, anti-obesity medications, antibiotics, and\u002For probiotic supplements in the 2 months preceding data collection;\n* Use of alcohol or tobacco;\n* Have limited mobility and a previous diagnosis of cardiopulmonary diseases;\n* Report current or previous (within the past two months) diarrhea during screening;\n* Have liver or kidney failure and uncontrolled endocrine disorders (hypothyroidism, hypogonadism, and adrenal insufficiency);\n* Have eating disorders or have undergone bariatric surgery.","ALL","45 Years","70 Years",{"count":18,"type":19},60,"ESTIMATED","INTERVENTIONAL",[22],"NA","The study evaluates the impact of a strict vegetarian diet combined with regular physical exercise and the use of probiotics on metabolic, inflammatory, and epigenetic parameters in patients with type 2 diabetes. It aims to determine the influence of these interventions on gut microbiota, glycemic control, body composition, insulin resistance, and quality of life.",[25,26,27,28],"Type 2 Diabetes Mellitus (T2DM)","Insulin Resistance","Inflamation","Gut Microbiomes",[30,26,27,31,32,33,34,35],"Type 2 Diabetes Mellitus","Metabolic Syndrome","Physical Exercise","Gut Microbiome","Plant-based Diet","Lifestyle Interventions","RECRUITING","2025-05-13",{"date":39,"type":40},"2025-05-18","ACTUAL",{"date":42,"type":40},"2022-11-22",{"date":44,"type":19},"2026-12",{"name":46,"class":47},"Maria Elizabeth Rossi da Silva","OTHER",""]