[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Max Nieuwdorp\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":13,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100554726",false,"NCT06502834","Effect of 4 Weeks of Oral D. Piger on Safety, Pharmacokinetics and Ethanol Metabolism in Overweight Individuals (2023)","PIGER","Inclusion:\n\nMale or (postmenopausal) females\n\n* Increased waist circumference (\\>102 cm men, 88\\>cm women)\n* Insulin resistance (HOMA\\>2.5)\n* 18-70 years\n\nExclusion Criteria:\n\n* Use of systemic medication (except for paracetamol), including antibiotics and pro-\u002Fprebiotics in the past three months or during the study period.\n* A history of a cardiovascular event\n* A history of cholecystectomy\n* Overt untreated gastrointestinal disease or abnormal bowel habits\n* Liver enzymes\\>2.5 fold higher than the upper limit of normal range\n* Smoking\n* Alcohol abuse","ALL","18 Years","70 Years",{"count":19,"type":20},20,"ESTIMATED","INTERVENTIONAL",[23],"PHASE1","The goal of the study is to determine the effect of supplementation of the d piger strain on intestinal ethanol production in individuals with overweight.\n\nThe investigators will perform a randomized trial in 2x10 participants to measure effects on ethanol in blood, and perform fecal analyses.",[26,27,28],"Obesity","Metabolic Syndrome","Steatosis of Liver","RECRUITING","2024-07-15",{"date":32,"type":33},"2024-07-16","ACTUAL",{"date":35,"type":33},"2024-05-01",{"date":37,"type":20},"2024-12-01",{"name":39,"class":40},"Max Nieuwdorp","OTHER",""]