[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Midwest Veterans' Biomedical Research Foundation\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":40},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100483085",false,"NCT05570448","Anti-Reflux Endoscopic TX Using APC (AREA) in GERD Patients: (The AREA Study)","Anti-Reflux Endoscopic Therapy Using Argon Plasma Coagulation (AREA) in Gastroesophageal Reflux Disease (GERD) Patients: A Single Center, Randomized, Sham, Controlled Trial (The AREA Study)","AREA21","Inclusion Criteria:\n\n* Chronic GERD symptoms (at least 1 typical symptom of GERD, i.e. heartburn or acid reflux\u002Fregurgitation at least twice a week) for last 6 months\n* Objective evidence of reflux disease (positive ambulatory pH study.)\n\nExclusion Criteria:\n\n* Patients unable to or unwilling to participate or consent.\n* Age \\\u003C18 years or \\>80 years.\n* Allergic or intolerant to PPI medications.\n* Large hiatal hernia \\> 3 cm and Hill grade IV.\n* Barrett's esophagus.\n* Esophageal stricture with any prior intervention.\n* Major motility disorder.\n* Eosinophilic esophagitis.\n* Gastroparesis documented by abnormal gastric emptying time.\n* Previous fundoplication, myotomy or LINX surgery.\n* Cirrhosis with esophageal and\u002For gastric varices.","ALL","18 Years","80 Years",{"count":20,"type":21},36,"ESTIMATED","INTERVENTIONAL",[24],"NA","This will be a randomized clinical trial examining the efficacy and safety of ARAT (intervention group) in patients with chronic GERD symptoms (typical symptoms of GERD, i.e. heartburn or acid reflux\u002Fregurgitation at least twice a week) for the last 6 months.\n\nPatients must have a positive pH test and a negative manometry (no treatment) procedure.",[27],"Gastro Esophageal Reflux","RECRUITING","2026-02-26",{"date":31,"type":32},"2026-02-27","ACTUAL",{"date":34,"type":32},"2022-02-15",{"date":36,"type":21},"2027-04-01",{"name":38,"class":39},"Midwest Veterans' Biomedical Research Foundation","OTHER",""]