[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Nicklaus Children's Hospital f\u002Fk\u002Fa Miami Children's Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":70},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100631628",false,"NCT07503158","Prospective Evaluation of Cardiac Point-of-Care Ultrasound (POCUS) Performed by PEM Fellows and Artificial Intelligence on Children With Pre-existing Cardiac Conditions.","Prospective Evaluation of Cardiac Point-of-Care Ultrasound (POCUS) Performed by PEM Fellows and Artificial Intelligence Interpretation Compared With a Complete Echocardiography in Children With Preexisting Cardiac Disease","POCUS-AI PEM","Inclusion Criteria:\n\n* Children aged 0-21 years\n* Preexisting cardiac disease\n* Participants are either evaluated in the ED or in the cardiology setting.\n\nExclusion Criteria:\n\n* Participant's clinical condition requires immediate life-saving interventions\n* New diagnosis of cardiac condition\n* Preexisting cardiac abnormality documented prior to the index encounter.","ALL","1 Month","21 Years",{"count":20,"type":21},200,"ESTIMATED","OBSERVATIONAL","The goal of this study is to prospectively assess the diagnostic agreement of PEM fellow-performed cardiac POCUS and of AI-assisted interpretation using the Exo Iris probe, as compared to a complete echocardiography for detecting left ventricular (LV) systolic dysfunction and pericardial effusion in children with preexisting cardiac disease.",[25],"Cardiac Anomalies",[27,28],"POCUS AI","Children","NOT_YET_RECRUITING","2026-04-02",{"date":32,"type":33},"2026-04-08","ACTUAL",{"date":35,"type":21},"2026-03-30",{"date":37,"type":21},"2028-03-30",{"name":39,"class":40},"Nicklaus Children's Hospital f\u002Fk\u002Fa Miami Children's Hospital","OTHER",1,{"id":43,"slug":4,"hasResults":10,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":10,"sex":16,"minAge":4,"maxAge":18,"enrollmentInfo":48,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":50,"conditions":51,"keywords":54,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":41},"100320986","NCT03458962","Diagnostic Odyssey: Whole Genome Sequencing (WGS)","Ending the Diagnostic Odyssey: Whole Genome Sequencing (WGS) to Identify Genetic Determinants of Previously Undiagnosed Disease in Children","Inclusion Criteria:\n\n* Symptomatic male or female children ages 0-21 who have un unknown medical condition thought to have an underlying genetic cause after parental consent has been obtained.\n* Willingness of referring provider or other qualified medical staff member to participate in this study by facilitating collection of biologic specimens and clinical information.\n* Patient whose medical condition can be reasonably attributed to a possible genetic etiology.\n* Patient have had at least one diagnostic test without a definite diagnosis.\n\nExclusion Criteria:\n\n* Unwillingness to consent to research.\n* Affected adults (\\>21 years of age), unless they are a biological relative of the affected child.\n* Any patient whose medical condition cannot be reasonably attributed to a possible genetic etiology or there is a prior diagnosis that explains the child's clinical presentation.",{"count":49,"type":21},1000,"The goal of this collaborative research is to study human genomes in children with suspected congenital disease, multiple-congenital anomalies and\u002For multi-organ disease of unknown etiology by understanding the potential value of Whole Genome Sequencing (WGS) in establishing genetic diagnosis. The study will examine diagnosis rates, changes in clinical care as a result of a genetic diagnosis, health economics including potential cost-effectiveness of WGS and patient and provider experience with genomic medicine.",[52,53],"Genetic Disease","Genetic Syndrome",[55,56,57,58,59,60],"Nicklaus Children's","Pediatric","Genomic","Precision Medicine","Biorepository","Rady Children's","RECRUITING","2024-11-06",{"date":64,"type":33},"2024-11-07",{"date":66,"type":33},"2018-02-20",{"date":68,"type":21},"2070-03",{"name":39,"class":40},""]