[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Notos Medical Limited\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100623439",false,"NCT07396649","Feasibility of Upper Airway Stimulation in OSA","Feasibility of Non-invasive Electrical Nerve Stimulation of the Upper Airway in Patients With Obstructive Sleep Apnoea","Inclusion Criteria:\n\n* Obstructive sleep apnoea diagnosis with an AHI of 15-50 events\u002Fhour recorded in the baseline polysomnography (PSG)\n* BMI \\\u003C 32 kg\u002Fm²\n* Age \\> 18 years old\n* Able to read, write, and speak Dutch with acceptable visual and auditory acuity\n* Able and willing to provide informed consent\n\nExclusion Criteria:\n\n* Presence of a cardiac pacemaker or implantable cardiac defibrillator or ventriculoperitoneal shunt\n* Central (non-obstructive) AHI episodes \\>5 events\u002Fhour recorded in the baseline PSG\n* Inability to sleep supine\n* Pregnancy\n* Inability to undergo DISE\n* Inability or unwillingness to shave under and around their chin and neck if appropriate\n* Known inability to complete PSG with a total sleep time of \\> 4 hours\n* The use of other neurostimulatory devices\n* A diagnosis of periodic leg movement disorder\n* Awake resting arterial oxygen saturation \\\u003C93% (suggesting possible hypoventilation)\n* Unstable, untreated coronary or peripheral artery disease\n* Severe arterial hypertension defined as a resting blood pressure (BP) of \\>180\u002F110mmHg\n* Currently employed as a professional driver\n* Any previous sleep-related driving accident\n* A past or current condition that in the opinion of the investigator contraindicates enrolment (e.g. chronic substance abuse, severe psychiatric disorders)","ALL","19 Years",{"count":18,"type":19},15,"ESTIMATED","INTERVENTIONAL",[22],"NA","Project Breathe 1 is a short-duration (5 month) pilot investigation to assess the safety and tolerability of non-invasive electrical stimulation in adults with obstructive sleep apnoea. The investigation is an unblinded, uncontrolled, single arm design.",[25],"Obstructive Sleep Apnoea (OSA)",[27,28,29],"obstructive sleep apnoea","OSA","sleep apnoea","RECRUITING","2026-02-05",{"date":33,"type":34},"2026-02-09","ACTUAL",{"date":36,"type":34},"2026-01-29",{"date":38,"type":19},"2026-07",{"name":40,"class":41},"Notos Medical Limited","INDUSTRY",""]