[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Spital Thurgau AG\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":64},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,38],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":4},"100630980",false,"NCT07494721","Effects of Training With a Pressure Cuff on Cellular Energy Activity","Influence of Short-Term Conventional Cuff-Assisted Training on Mitochondrial Capacity: A Non-Invasive Investigation","Inclusion:\n\n* Medically confirmed generalized deconditioning with reduced muscle strength\n* Medical certification of suitability for functional lower-extremity strength training\n* Written informed consent after an adequate reflection period\n\nExclusion:\n\n* Unstable arrhythmias, myocardial ischemia, symptomatic blood pressure drops or hypertension (\\>160\u002F100 mmHg despite medication)\n* History of thrombosis or acute swelling\u002Fskin discoloration of the legs\n* Dizziness, confusion, cyanosis, or unexplained fatigue\n* Participant's wish to withdraw or not participate","ALL","18 Years",{"count":18,"type":19},51,"ESTIMATED","INTERVENTIONAL",[22],"NA","This study investigates low-load, cuff-assisted training to improve mitochondrial capacity. The intervention is carried out using automated pressure cuffs, applying an individualized pressure of 70% of the limb occlusion pressure. This approach reflects the current scientific consensus for safe and effective use in clinical populations.\n\nWithin a rehabilitation setting, two training modalities are compared: intermittent strength training and alternating continuous endurance training. Muscle oxygen saturation is measured non-invasively using near-infrared spectroscopy.",[25],"Physical Deconditioning","NOT_YET_RECRUITING","2026-03-26",{"date":29,"type":30},"2026-04-01","ACTUAL",{"date":32,"type":19},"2026-07",{"date":34,"type":19},"2026-12",{"name":36,"class":37},"Spital Thurgau AG","OTHER",{"id":39,"slug":4,"hasResults":10,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":4,"eligibilityCriteria":43,"healthyVolunteers":10,"sex":15,"minAge":44,"maxAge":45,"enrollmentInfo":46,"targetDuration":4,"studyType":20,"phases":48,"briefSummary":49,"conditions":50,"keywords":52,"overallStatus":54,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":63},"100522000","NCT06076902","Patch Study (Patch-augmented Rotator Cuff Repair)","Patch Study: a Single-center, Prospective, Single-blind, Randomized, Two-arm Controlled Study of Outcomes Following Synthetic Polyester Patch-augmented Rotator Cuff Repair","Inclusion Criteria:\n\n* Adults with massive rotator cuff tear\n* Tear must affect at least two tendons\n* Primary surgery only\n* Origin of tear can be either degenerative or traumatic\n* German language speaking\n\nExclusion Criteria:\n\n* Fatty infiltration grade 4 (according to Goutallier)\n* Bilateral tears\n* Cases of arthritis or severe osteoarthritis\n* Structural or pathological condition of the bone or soft tissue that could impair healing\n* Unable or unwilling to restrict activities to prescribed levels or follow rehabilitation guidelines\n* Unable or unwilling to give consent (language barrier or cognitive impairment)\n* Unwilling or unable to be assessed at 1- and 2-year follow-up assessment visits","30 Years","75 Years",{"count":47,"type":19},300,[22],"This single-center, prospective, randomized controlled study will compare patients allocated to two treatment arms who are undergoing surgery to repair rotator cuff tears: (1) arthroscopic rotator cuff reconstruction using fixation with anchors augmented with a synthetic polyester patch, and (2) arthroscopic rotator cuff reconstruction using fixation with anchors and no augmentation with a synthetic polyester patch. The primary objective is to compare complications (primarily retear rates) and the secondary objective is to compare mid- and long-term clinical and radiological outcomes using standard orthopedic assessments, such as the subjective shoulder value and the Constant-Murley score.",[51],"Rotator Cuff Tears",[53],"Rotator Cuff Repair","RECRUITING","2023-10-04",{"date":57,"type":30},"2023-10-11",{"date":59,"type":30},"2023-04-06",{"date":61,"type":19},"2027-04-30",{"name":36,"class":37},1,""]