[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"State Scientific Centre of Coloproctology, Russian Federation\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":125},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,47,72,98],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":16,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100613566",false,"NCT07268261","Combined Method of Surgical Treatment of Anal Fissure","Inclusion Criteria:\n\n* • Patients with chronic anal fissure with spasm of anal sphincter\n\nExclusion Criteria:\n\n* • Inflammatory diseases of the colon\n\n  * Pectenosis\n  * Previous surgical interventions on the anal canal\n  * IV grade internal and external hemorrhoids\n  * Rectal fistula\n  * Severe somatic diseases at the decompensation stage\n  * Pregnancy and lactation\n  * Anal sphincter insufficiency\n  * Chronic paraproctitis\n  * Individual intolerance and hypersensitivity to botulinum toxin\n  * Myasthenia gravis and myasthenic syndromes\n  * History of allergic reaction to anticoagulants.\n  * Blood diseases (thrombocytopenia, splenomegaly, etc.)","ALL","18 Years","70 Years",{"count":18,"type":19},122,"ESTIMATED","INTERVENTIONAL",[22],"NA","The purpose of this study is to improve treatment outcomes for patients with chronic anal fissure.",[25],"Chronic Anal Fissure",[27,28,29,30,31,32,33],"Fissure in Ano","Anal fissure","botulinum toxin A","Chronic anal pain","Fecal incontinence","Spasm of the internal sphincter","Anal sphincter insufficiency","RECRUITING","2025-12-03",{"date":37,"type":38},"2025-12-05","ACTUAL",{"date":40,"type":38},"2023-09-01",{"date":42,"type":19},"2026-09-01",{"name":44,"class":45},"State Scientific Centre of Coloproctology, Russian Federation","OTHER_GOV",1,{"id":48,"slug":4,"hasResults":10,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":20,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":46},"100552175","NCT06469671","Effectiveness of Artificial Intelligence - Assisted Colonoscopy in Colorectal Neoplasms","Artificial Intelligence - Assisted Colonoscopy in Diagnosis of Colorectal Neoplasms: Russian Multicenter Randomised Open - Label Trial","ArtInCol","Inclusion Criteria:\n\n* Screening coloscopy is needed\n\nExclusion Criteria:\n\n* Indications for colonoscopy\n* Previously detected colorectal neoplasms\n* Previously performed colorectal surgery\n* Colorectal cancer\n* Inflammatory bowel disease","90 Years",{"count":56,"type":19},1000,[22],"The primary goal of this study is to estimate the effectiveness of a medical decision support system based on artificial intelligence in the endoscopic diagnosis of benign tumors.\n\nResearchers will compare Adenoma detection rate between \"artificial intelligence - assisted colonoscopy\" and \"conventional colonoscopy\" groups to evaluate the clinical effectiveness of artificial intelligence model.",[60,61,62],"Colonic Neoplasms","Colonic Polyp","Diagnosis","NOT_YET_RECRUITING","2024-06-17",{"date":66,"type":38},"2024-06-21",{"date":68,"type":19},"2024-07",{"date":70,"type":19},"2024-12",{"name":44,"class":45},{"id":73,"slug":4,"hasResults":10,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":4,"enrollmentInfo":78,"targetDuration":80,"studyType":81,"phases":4,"briefSummary":82,"conditions":83,"keywords":88,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":46},"100477346","NCT05495776","Prospective Multicenter Registry Study to Assess the Frequency of Lynch Syndrome Among Patients With Colorectal Cancer","MSIRus22","Inclusion Criteria:\n\n* Provision of written informed consent;\n* Patients with histologically verified colon adenocarcinoma or patients with histologically verified synchronous neoplasms who have not previously received treatment for a second tumor;\n* Age ≥ 18 years;\n* Absence of antitumor treatment for a real tumor (it is allowed to include patients who have a history of antitumor treatment for other malignant tumors, if the period after treatment is more than 12 months).\n* The ability of the patient, according to the Researcher, to fulfill the requirements of the Protocol;\n\nExclusion Criteria:\n\n\\- Patients receiving chemotherapy or radiotherapy for colon cancer at the time of screening",{"count":79,"type":19},2500,"5 Years","OBSERVATIONAL","Prospective multicenter registry study to assess the frequency of Lynch syndrome among patients with colorectal cancer in Russia",[84,85,86,87],"Colorectal Cancer","Lynch Syndrome","Hereditary Colorectal Cancer","MSI",[84,85,86,87,89],"Frequency","2022-10-24",{"date":92,"type":38},"2022-10-25",{"date":94,"type":38},"2022-08-01",{"date":96,"type":19},"2028-12-31",{"name":44,"class":45},{"id":99,"slug":4,"hasResults":10,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":4,"eligibilityCriteria":103,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":16,"enrollmentInfo":104,"targetDuration":4,"studyType":20,"phases":106,"briefSummary":108,"conditions":109,"keywords":110,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":124},"100351378","NCT03855046","Complex Treatment of a Chronic Anal Fissure","A Comparative Efficacy and Safety Study of Lateral Subcutaneous Sphincterotomy and Botulinum Toxin Type A in the Treatment of Chronic Anal Fissure","Inclusion Criteria:\n\n* Patients with chronic anal fissure\n\nExclusion Criteria:\n\n* Inflammatory diseases of the colon\n* Pectenosis\n* Previous surgical interventions on the anal canal\n* IV grade internal and external hemorrhoids\n* Rectal fistula\n* Severe somatic diseases at the decompensation stage\n* Pregnancy and lactation\n* Individual intolerance and hypersensitivity to botulinum toxin\n* Myasthenia gravis and myasthenia-like syndromes\n* Anal sphincter insufficiency",{"count":105,"type":19},340,[107],"PHASE4","This study is aimed at studying the efficacy and safety of treating chronic anal fissure with botulinum toxin versus lateral subcutaneous sphincterotomy.",[27],[111,28,112,29,113,114,30,31,32,33,115],"Internal sphincterotomy","Chronic anal fissure","proctologic diseases","surgical treatment","randomized","2022-01-26",{"date":118,"type":38},"2022-01-27",{"date":120,"type":38},"2019-09-01",{"date":122,"type":19},"2022-11-01",{"name":44,"class":45},7,""]