[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Sudarshan Jadcherla\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100525204",false,"NCT06118697","Feasibility of Aerodigestive Stimulation Therapy Trial","Safety and Feasibility of Aerodigestive Stimulation Therapy in Infants With Complex Feeding Difficulties","FAST","Inclusion Criteria:\n\n* NICU infant ≥37 weeks postmenstrual age not taking full oral feeds\n* Consult to Neonatal \\& Infant Feeding Disorder Program for oral feeding difficulty with diagnostic manometry ordered\n* Presence of peristaltic and sphincteric reflexes at initial manometry\n\nExclusion Criteria:\n\n* Potentially lethal chromosomal anomalies\n* Craniofacial malformations\n* Foregut malformations","ALL","1 Day","8 Months",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this study is to demonstrate safety, feasibility, and efficacy of a novel pharyngo-esophageal stimulation technique in restoring aerodigestive and swallowing functions in select infants at-risk for chronic gavage tube feeding or gastrostomy. The main aims are:\n\n* To provide consistent activation of deglutition (the process of swallowing), swallowing-airway interactions, and peristalsis in order to decrease the risk of home tube feeding.\n* To examine whether physical and manometric evidence-guided interventions and biofeedback will improve compliance, minimize parental stress, and increase satisfaction and perceived self-confidence with infant feeding.\n\nParticipants will have weekly pharyngo-esophageal stimulation guided by High Resolution Impedance Manometry (HRIM) for 4 weeks or until discharge, oral nutritive stimulation of at least 5 mL of prescribed milk with each feed, and weekly parental education and feedback regarding feeding progress.",[27],"Feeding Disorder Neonatal",[29,30,31,32],"Chronic tube feeding","Gastrostomy","Deglutition","Esophageal manometry","RECRUITING","2026-04-29",{"date":36,"type":37},"2026-05-05","ACTUAL",{"date":39,"type":37},"2024-02-05",{"date":41,"type":21},"2028-11-01",{"name":43,"class":44},"Sudarshan Jadcherla","OTHER",""]