[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Thomayer University Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":40},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":4,"maxAge":4,"enrollmentInfo":16,"targetDuration":19,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":24,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100452958",false,"NCT05178277","Czech AATD Registry","Czech Alpha-1 Antitrypsin Deficiency Registry, the National Observational Study.","Inclusion Criteria:\n\n* Patients with alpha-1-antitrypsin deficiency\n\nExclusion Criteria:\n\n* Patient disagreement with inclusion in the study","ALL",{"count":17,"type":18},300,"ESTIMATED","20 Years","OBSERVATIONAL","Alpha-1-antitrypsin deficiency is the most common congenital disease of the respiratory system, leading to early pulmonary emphysema or bronchiectasis. Pulmonary involvement significantly accelerates active cigarette smoking. Patients with alpha-1-antitrypsin deficiency may also have liver cirrhosis, vasculitis, skin or intestinal disorders.\n\nThe AATD Registry is a non-interventional multicenter retrospective prospective longitudinal follow-up of patients with alpha-1-antitrypsin deficiency.\n\nThe aim of the AATD National Registry is to collect and analyze clinical data in patients with alpha-1 antitrypsin deficiency.",[23],"Alpha-1-antitrypsin Deficiency",[25,26,27],"Alpha-1-antitrypsin deficiency","AATD","national registry","RECRUITING","2021-12-16",{"date":31,"type":32},"2022-01-05","ACTUAL",{"date":34,"type":32},"2018-01-01",{"date":36,"type":18},"2035-12-31",{"name":38,"class":39},"Thomayer University Hospital","OTHER",""]