[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Turgutlu State Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":53},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":5},"100613519",false,"NCT07267650","iPACK Block vs. Periarticular Infiltration for TKA Pain Control","Postoperative Analgesic Outcomes of iPACK Block Versus Periarticular Infiltration in Total Knee Arthroplasty: A Retrospective Cohort Study","Inclusion Criteria:\n\n* American Society of Anesthesiologists (ASA) physical status II-III.\n* Scheduled for elective, primary, unilateral total knee arthroplasty for osteoarthritis.\n* Able to provide written informed consent.\n\nExclusion Criteria:\n\n* Patient refusal to participate or contraindication to regional anesthesia.\n* Known allergy to any study medications (local anesthetics, NSAIDs, tramadol, morphine, paracetamol).\n* History of chronic opioid use (defined as daily use for \\>3 months)\n* Pre-existing peripheral neuropathy in the operative limb.\n* Severe renal or hepatic insufficiency.\n* Cognitive impairment preventing the use of pain scales or questionnaires.\n* Revision or bilateral knee arthroplasty.","ALL","18 Years","80 Years",{"count":19,"type":20},100,"ESTIMATED","OBSERVATIONAL","This study aims to retrospectively compare two different multimodal analgesic techniques for pain management after total knee arthroplasty (TKA). The primary purpose is to evaluate whether a combination of two specific nerve blocks administered by an anesthesiologist (Femoral Triangle Block + iPACK block) resulted in superior postoperative pain control compared to a hybrid combination of a nerve block and a local infiltration administered by the surgeon (FTB + Periarticular Infiltration \\[PAI\\]).\n\nThe hypothesis is that the FTB + iPACK combination is associated with a significant reduction in Numeric Rating Scale (NRS) pain scores with movement at 24 hours postoperatively. This is a retrospective, observational cohort study conducted at a single center, involving medical records of patients who underwent primary unilateral TKA. Data from patients who received either FTB + iPACK or FTB + PAI as part of their standard clinical care will be extracted and analyzed retrospectively.",[24,25],"Pain, Postoperative","Osteoarthritis, Knee \u002F Osteoarthritis, Hip",[27,28,29,30,31,32,33,34,35,36,37,38,39,40],"Total Knee Arthroplasty","TKA","Postoperative Pain","Pain Management","Analgesia","Nerve Block","Femoral Triangle Block","FTB","iPACK block","Local Infiltration Analgesia","Timed Up and Go Test","Straight Leg Raise","Periarticular Infiltration","Regional Anesthesia","NOT_YET_RECRUITING","2026-05-28",{"date":44,"type":45},"2026-06-01","ACTUAL",{"date":47,"type":20},"2026-05-01",{"date":49,"type":20},"2026-08-01",{"name":51,"class":52},"Turgutlu State Hospital","OTHER",""]