[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Université NAZI BONI\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100586206",false,"NCT06912360","Continous Positive Airway Pressure (CPAP) Support for Acute Hypoxemic Respiratory Failure in Burkina Faso","Use of (Continous Positive Airway Pressure) CPAP in the Management of Acute Hypoxemic Respiratory Failure","Inclusion Criteria:\n\nAll patients aged 18 years and older will be included in the study if they meet at least one of the following criteria :\n\n* Acute respiratory distress, defined as dyspnea respiratory rate ≥ 25 cycles\u002Fmin\n* Hypoxemia, defined as the need for more 6 liters of oxygen to maintain an oxygen saturation (SpO2) of ≥ 92%. The fraction of inspired oxygen (FiO2) will be estimated using the 3% rule.\n\nExclusion Criteria:\n\nPatients with any of the following criteria will not be included in the study:\n\n* Pregnant or breastfeeding women\n* Persons deprived of their liberty\n* Exacerbation of asthma, chronic obstructive pulmonary disease, or another chronic respiratory disease\n* Moderate to large amount of unilateral or bilateral undrained pleural effusion\n* Contraindication to CPAP: patient refusal, undrained pneumothorax, chest injury, repeated or large vomiting, upper gastrointestinal bleeding, craniofacial trauma, severe upper airway obstruction, or tetraplegia in the initial phase\n* Cardiac arrest, severe arrhythmias, shock requiring the use of vasopressors (norepinephrine, adrenaline, dopamine)\n* Altered level of consciousness (Glasgow Coma Scale score \\\u003C 13), repeated seizures, or status epilepticus\n* Medical decision to limit treatment: no intubation, no admission to intensive care\n* Refusal to participate in the study or participation in another interventional study on respiratory distress or acute respiratory failure.","ALL","18 Years",{"count":18,"type":19},240,"ESTIMATED","INTERVENTIONAL",[22],"NA","Acute respiratory failure (ARF) is a frequent medical emergency, involving high costs for health organizations and patients who often require intensive care and respiratory assistance. According to an international study, 61% of hypoxemic patients in intensive care receive invasive ventilation \\[3\\]. Invasive mechanical ventilation is often unavailable in low-income countries and non-invasive ventilatory supports such as continuous positive airway pressure (CPAP) and high-flow oxygen therapy (HFO) were very useful during the COVID-19 pandemic. They reduced the rate of intubation and ICU admissions. In addition, CPAP can be used without a ventilator, no electricity is required. So, it could be a support of choice in low-income countries.\n\nUsed of Boussignac-type CPAP could potentially reduce the recourse to intubation in patients with acute hypoxemic respiratory failure in a context where access to invasive ventilation remains very limited.",[25],"Acute Respiratory Failure",[27,28,29],"CPAP","Acute hypoxemic respiratory failure","Africa","RECRUITING","2025-07-23",{"date":33,"type":34},"2025-07-28","ACTUAL",{"date":36,"type":34},"2025-07-09",{"date":38,"type":19},"2026-02-20",{"name":40,"class":41},"Université NAZI BONI","OTHER",4,""]