[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Zhide Liang\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":48},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":4},"100636614",false,"NCT07567976","Tai Chi Intervention for Balance Function in Older Adults: Predictive and Modifying Roles of Circadian Age","Effects of Tai Chi on Balance Function in Community-Dwelling Older Adults: A Randomized Controlled Trial Examining the Predictive and Modifying Roles of Circadian Age, With Multi-Omics and Brain Function Assessments","Inclusion Criteria:\n\n* Aged 55 years or older\n* Community-dwelling\n* Able to walk independently (assistive devices such as canes are permitted)\n* Berg Balance Scale (BBS) score ≤52 at screening\n* Able to understand and follow verbal instructions\n* Willing to wear a wrist accelerometer continuously for 7 days at baseline\n* Willing to accept random group assignment\n* Willing to undergo blood collection during the study\n* Provides written informed consent\n\nExclusion Criteria:\n\n* Regular Tai Chi or yoga practice (more than once per week) within the past 6 months\n* Severe cognitive impairment (Montreal Cognitive Assessment \\[MoCA\\] score \\\u003C20 at screening, or previously diagnosed dementia)\n* Unstable cardiovascular disease (myocardial infarction, stroke, or hospitalization within the past 3 months)\n* Severe musculoskeletal disease that limits exercise participation\n* Neurological diseases affecting balance (e.g., Parkinson's disease, severe peripheral neuropathy)\n* Currently participating in another exercise intervention study\n* Planned surgery or extended absence during the study period\n* Contraindications to functional near-infrared spectroscopy (fNIRS) examination (e.g., scalp injury, metallic implants in the head region)\n* Severe psychiatric illness (e.g., schizophrenia, bipolar disorder)\n* Considered unable to safely participate in moderate-intensity physical activity as judged by the study physician or attending healthcare provider",true,"ALL","55 Years",{"count":19,"type":20},90,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study investigates the effects of a 12-week Tai Chi intervention on balance function in community-dwelling older adults. Participants are randomly assigned to either a Tai Chi exercise group or a health education control group. The primary outcome is balance function measured by the Berg Balance Scale. Secondary outcomes include physical function, psychological well-being, cognitive function, and sleep quality. The study also explores the predictive and modifying roles of baseline circadian age on intervention outcomes.",[26,27,28],"Aging","Postural Balance","Accidental Falls",[30,31,32,33,34,35],"Tai Chi","Tai Ji Quan","Mind-Body Exercise","Older Adults","Fall Prevention","Circadian Rhythm","NOT_YET_RECRUITING","2026-06-30",{"date":39,"type":40},"2026-07-02","ACTUAL",{"date":42,"type":20},"2026-06-01",{"date":44,"type":20},"2027-03",{"name":46,"class":47},"Zhide Liang","OTHER",""]