[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Zhifen Liu\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100572055",false,"NCT06728280","Efficacy and Safety of DTMS in Adolescent Major Depressive Disorder","Efficacy and Safety of Deep Transcranial Magnetic Stimulation in Adolescent Major Depressive Disorder: a Prospective Double-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients of all genders, aged between 11 and 23 years old, and right-handedness.\n* In accordance with the diagnostic criteria for the major depressive disorder of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5).\n* The current major depressive episode (MDE) must be confirmed using the Mini International Neuropsychiatric Interview (M.I.N.I).\n* Beck Depression Inventory, Second Edition (BDI-II): total BDI-II score\\> 13 at screening.\n* Subjects who can understand and are willing to strictly follow the clinical trial protocol to complete this study and sign informed consent.\n\nExclusion Criteria:\n\n* A diagnosis of other psychiatric disorders in the DSM-5.\n* Clinically significant laboratory abnormality or medical condition, that in the opinion of the investigator would hinder the subject in completing the procedures required by the study.\n* History of significant neurologic disease, including subdural hematoma, brain tumor, unexpected seizure\u002Fepilepsy disorder, or history of significant head trauma.\n* Have obvious suicide risk, or have actual suicide behavior within 6 months before the screening.\n* History of treatment with electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), transcranial Direct Current Stimulation (tDCS), or transcranial Alternating Current Stimulation (tACS) treatments for any disorders.\n* There are contraindications to magnetic resonance imaging (MRI) scanning or TMS treatment, such as metal or electronic instruments.\n* Participation in any investigational drug trial within 6 months before the baseline visit.\n* Other conditions that are not suitable for the study object in the researcher's judgment.","ALL","11 Years","23 Years",{"count":19,"type":20},100,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this randomized controlled trial is to explore the efficacy and safety of two different dTMS devices in adolescent depression: deep TMS H1 coil and deep TMS H7 coil.\n\nThe main questions it aims to answer are:\n\nType of study: Clinical trial. Participant population: Adolescents with major depressive disorder (MDD). Objective: To explore whether the H7 coil is no less effective than the H1 coil for adolescents with MDD, further providing clinicians with additional treatment options for patients.",[26],"Major Depressive Diorder",[28,26,29],"deep transcranial magnetic stimulation","adolescents","RECRUITING","2025-03-10",{"date":33,"type":34},"2025-03-12","ACTUAL",{"date":36,"type":34},"2024-12-31",{"date":38,"type":20},"2026-06-30",{"name":40,"class":41},"Zhifen Liu","OTHER",2,""]