[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"prof. dr. Rik Schrijvers\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":69},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100613077",false,"NCT07261891","Ex Vivo Evaluation of JAK-inhibitor and Gene Therapeutical Approach in JAK-STAT Related Disorders","Ex Vivo Evaluation of JAK-inhibitor and Gene Therapeutical Approach in JAK-STAT Related Disorders (JAKarta Study)","JAKarta","Inclusion Criteria:\n\n* Cases (A): adult patients presenting with a genetically confirmed or highly suspected disorder leading to an exagerated JAK-STAT pathway.\n* Controls (B): participants eligible for inclusion in this study must fall in one of the following categories:\n* Healthy controls (without immune-mediated disease)\n\nExclusion Criteria:\n\n* Children (\\\u003C 18 years at time of recruitment)\n* Persons unable or unwilling to give informed consent",true,"ALL","18 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","The investigators want to study the JAK-inhibitors and their impact on the immune system and evaluate the potential of a gene-therapeutic strategy",[27],"Primary Immunodeficiency Diseases (PID)",[29,30,31],"JAK inhibitors","STAT1 gain-of-function","gene therapy","RECRUITING","2025-11-28",{"date":35,"type":36},"2025-12-03","ACTUAL",{"date":38,"type":36},"2024-11-21",{"date":40,"type":21},"2030-12-01",{"name":42,"class":43},"prof. dr. Rik Schrijvers","OTHER",1,{"id":46,"slug":4,"hasResults":10,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":44},"100570969","NCT06714149","Impacts of Nitrogen Deposition in the Natural Environment on Pollen Allergy in Belgium","NITROPOL-BE","Inclusion Criteria:\n\n* Positive skin prick test for grass and\u002For birch pollen\n\nExclusion Criteria:\n\n* Desensitization therapy during the last two years",{"count":52,"type":21},200,[24],"The investigators want to study the effect of environmental nitrogen enrichment on the allergy burden in pollen-sensitized subjects.",[56],"Pollen Allergy",[58,59,60],"Nitrogen","Pollution","Pollen allergy","2024-12-02",{"date":63,"type":36},"2024-12-03",{"date":65,"type":36},"2022-06-29",{"date":67,"type":21},"2025-04",{"name":42,"class":43},""]