[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"all-adult-patients-undergoing-an-otolaryngology-procedure-with-inhaled-methoxyflurane-as-an-adjunct-to-topical-or-local-anesthesia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:all-adult-patients-undergoing-an-otolaryngology-procedure-with-inhaled-methoxyflurane-as-an-adjunct-to-topical-or-local-anesthesia":37},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":26,"lastUpdatePostDateStruct":27,"startDateStruct":30,"completionDateStruct":32,"leadSponsor":34,"locationsCount":4},"100593241",false,"NCT07003880","Penthrox in Otolaryngology","Inhaled Methoxyflurane for In-Office Procedures in Otolaryngology","PenthroxOTL","Inclusion Criteria:\n\n* All adult patients undergoing any of the following procedures with inhaled methoxyflurane as an adjunct to topical or local anesthesia:\n\n  * Skin lesion excision or reconstruction\n  * Fine or core needle aspiration biopsy\n  * Mucosal biopsy\n  * Laryngeal injection or biopsy\n  * Myringotomy with or without tympanostomy tube insertion\n  * Inferior turbinate reduction\n  * Septal button insertion\n\nExclusion Criteria:\n\n* Patient unable to complete the post-procedure questionnaire (either due to time constraints, neurocognitive impairment, etc.)\n* Presence of any contraindications to inhaled methoxyfluorane per product monograph:\n\n  * Patients less than 18 years of age\n  * Pregnancy, intended pregnancy, or current breast-feeding\n  * Inadequate patient understanding or lack of cooperation\n  * Decreased level of consciousness or head injury\n  * History of clinically significant renal impairment, e.g., reduced renal output\n  * History of liver dysfunction following previous exposure to halogenated anesthetics\n  * Current use of tetracycline antibiotics\n  * Personal or genetic history of malignant hyperthermia\n  * Muscular dystrophy","ALL","18 Years",{"count":19,"type":20},50,"ESTIMATED","OBSERVATIONAL","Our objective is to explore the use of methoxyflurane anesthesia as an adjunct analgesic to local anesthesia during in-office otolaryngology procedures in a prospective pilot study. The main outcome of this study will be patient satisfaction with the medication and analgesia. Secondary outcomes will include level of sedation and analgesia, patient-reported post-procedural pain levels, and any reported adverse events.",[24],"All Adult Patients Undergoing an Otolaryngology Procedure With Inhaled Methoxyflurane as an Adjunct to Topical or Local Anesthesia","NOT_YET_RECRUITING","2025-05-26",{"date":28,"type":29},"2025-06-04","ACTUAL",{"date":31,"type":20},"2025-06-01",{"date":33,"type":20},"2027-06-01",{"name":35,"class":36},"Sir Mortimer B. Davis - Jewish General Hospital","OTHER",""]