Antineutrophil Cytoplasmic Antibody Associated Vasculitis

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Review clinical trials related to Antineutrophil Cytoplasmic Antibody Associated Vasculitis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

The primary objective of this study is to evaluate the long-term safety of avacopan in participants with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).

Participants needed: 300
Trial details
Phase: Phase 4Age: 18-100Biological sex: AllType: InterventionalSponsor: AmgenUpdated: Jun 18, 2026Locations: 80
Eligibility criteria

Participants has provided informed consent before initiation of any study-specif... [+5]

Alveolar hemorrhage requiring invasive pulmonary ventilation support anticipated... [+26]

Status: Recruiting

A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

This is a Phase 1/2, open-label, multi-center, multi-cohort, non-randomized dose escalation and dose expansion basket study to determine the safety and tolerability of NKX019 (allogeneic CAR NK cells targeting CD19) in participants with autoimmune diseases.

Participants needed: 240
Trial details
Phase: Phase 1, Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Nkarta, Inc.Updated: Jun 4, 2026Locations: 17
Eligibility criteria

Age ≥18 and ≤75 [+25]

eGFR < 45 ml/min/1.73m2 [+37]

Status: Recruiting

CC-97540 in Patients With Antineutrophil Cytoplasmic Antibody-associated Vasculitis

The purpose of this study is to evaluate the safety of CC-97540 in relapsed or refractory severe antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis.

Participants needed: 12
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Marcela V. Maus, M.D.,Ph.D.Updated: May 15, 2026Locations: 1
Eligibility criteria

Able to voluntarily provide written informed consent prior to the performance of... [+17]

Current or historical positivity for a glomerular basement membrane antibody. [+15]