Ataxia - Other

4

Review clinical trials related to Ataxia - Other. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Vibrotactile Balance Belt Effect on Improving Gait

This study will examine the effect of using a vibrotactile feedback implemented into a belt, at improving gait in those with gait disorders.

Participants needed: 90
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Johns Hopkins UniversityUpdated: Mar 27, 2026Locations: 2
Eligibility criteria

Age 18-80 years old [+4]

Previous Vestibular Rehabilitation Therapy (VRT) finished less than 2 months ago [+2]

Status: Recruiting

At Home Use of Stimulation Suits for Managing MS Symptoms

This study is being carried out at Multiple Sclerosis (MS) centers to evaluate whether a full-body stimulation suit at home can help people with Multiple Sclerosis (pwMS) reduce symptoms like spasticity (muscle stiffness) and ataxia (poor coordination), and improve daily functioning. Can pwMS who experience spasticity or ataxia benefit from using a stimulation suit for 6 weeks? Researchers will compare two groups: an intervention group (who will use the suit) and a control group (who will not use the suit). Participants in the intervention group will: * Wear the suit for 6 weeks in total every day or every other day (1 week during their MS center admission and 5 weeks at home). * Receive their usual care in addition to wearing the suit. * Undergo clinical tests at the MS center after 1 week and 6 weeks of stimulation. Participants in the control group will: * Receive their usual care. * Undergo clincial tests at the same time points as the other group.

Participants needed: 70
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Daphne KosUpdated: Feb 6, 2026Locations: 2
Eligibility criteria

Eligible participants must have ataxia or spasticity alongside impairments in up... [+2]

Implanted devices (like pacemaker, Baclofen pump, neurostimulator, defibrillator... [+7]

Status: Not yet recruiting

Structural Validity and Inter-rater Reliabitiliy of the Ataxia Trunk, Lower And Upper Extremity Scale (ATLAS)

Ataxia is a neurological disorder affecting coordination, caused by damage to the cerebellum, brainstem, or related pathways. It can be hereditary (e.g., Friedreich's ataxia) or acquired (e.g., multiple sclerosis, stroke). Though rare, ataxia significantly impacts quality of life and independence. Treatments are limited and mainly focus on multidisciplinary rehabilitation. Accurate assessment is essential, yet current tools like Scale for the Assessment and Rating of Ataxia (SARA) have limitations. This study aims to validate a new scale, named the Ataxia Trunk, Lower And upper extremity Scale (ATLAS), through Rasch analysis, to develop a shorter, reliable version. It will assess internal consistency, construct validity, and inter-rater reliability. For the valitdity part, statistics will be used (1) to see if the different items of the scale are indeed different and complementary to each other, and (2) to compare the results of this scale with other scales already known and valid (SARA, Trunk Impairment Scale (TIS) and Functional Impairment Measurement(FIM)). Secondly, the investigators would like to know whether ATLAS is reliable. In this particular case, the reliability being assessed is inter-rater reliability, i.e. whether all raters give the same score on the items performed by the patient. To carry out such a study, 64 people will be needed to achieve these goals. Each person will complete the 20 items of the ATLAS scale, those of a trunk motor capacity assessment (TIS), and will evaluate his or her functional independence (FIM).

Participants needed: 64
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Haute Ecole de Santé VaudUpdated: Aug 13, 2025
Eligibility criteria

Be adults [+3]

Muscle group strength < 3 on the Medical Research Council (MRC) scale [+2]

Status: Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures for rare diseases. The CoRDS team works with patient advocacy groups, individuals and researchers to help in the advancement of research in over 7,000 rare diseases. The registry is free for patients to enroll and researchers to access. Visit sanfordresearch.org/CoRDS to enroll.

Participants needed: 20,000
Trial details
Biological sex: AllType: ObservationalSponsor: Sanford HealthUpdated: May 29, 2025Locations: 2Duration: 100 Years
Eligibility criteria

Diagnosis of a rare disease, a disease of unknown prevalence, undiagnosed or an...

Diagnosis of a disease which is not rare