[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"auto-immune-hepatitis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:auto-immune-hepatitis":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100574586",false,"NCT06761209","Is Negativity of Autoantibodies a Marker of Severity in Auto-immune Hepatitis?","Is Negativity of Autoantibodies a Marker of Severity in Auto-immune Hepatitis","HAI-NEG","Inclusion Criteria:\n\n* \\- Any patient over 18 years old\n* Patient followed at Hôpital Saint-Antoine or treated for HAI or in Guadeloupe within the framework of the CCRD Filfoie for an acute or chronic AIH under immunosuppressive treatment\n* Patient affiliate or beneficiary of a social security scheme\n* Free, informed and written consent signed by the patient and the investigator\n\n  o exclusion criteria: - Patient under 18 years old\n* Patient not able to give his\u002Fher consent\n* Viral hepatitis: viruses A to E, Epstein-Barr virus, cytomegalovirus and herpes simplex virus\n* Isolated primary biliary cholangitis\n* Isolated primary sclerosing cholangitis\n* Drug-induced liver injury\n* Wilson disease\n* Alcoholic hepatitis\n* Hemochromatosis\n* Sickle cell disease and heart liver\n* Non-alcoholic steato-hepatitis","ALL","18 Years",{"count":19,"type":20},100,"ESTIMATED","OBSERVATIONAL","Evaluate the proportion of seronegative auto-immune hepatitis and a possible relationship with the severity of the disease. Criteria of severity will be defined by corticodependance, corticoresistance and a severe form of the disease at diagnosis (cirrhosis or fulminant hepatitis). In case of predominant seronegative forms, other auto-antibodies related to this auto-immue hepatitis will be searched.",[24],"Auto-immune Hepatitis",[26,27,28,29],"autoantibodies","auto-immune hepatitis","prognosis","afrocaribbean population","RECRUITING","2024-12-30",{"date":33,"type":34},"2025-01-07","ACTUAL",{"date":36,"type":34},"2022-07-01",{"date":38,"type":20},"2026-12",{"name":40,"class":41},"Centre Hospitalier Universitaire de la Guadeloupe","OTHER",2,""]