[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"autologous-cartilage-grafting\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:autologous-cartilage-grafting":47},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":14,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100545635",false,"NCT06384469","The Impact of Rhinoplasty Approach and Used Autologous Cartilage Grafts on the Nasal Skin-soft Tissue Envelope Metabolism","Inclusion Criteria:\n\n* Adult patients undergoing primary functional rhinoplasty who comply with the study\n* Adult patients undergoing primary functional rhinoplasty who have singed the informed consent, previously approved by the ethics commitee.\n\nExclusion Criteria: -\n\n* patients with previous surgical procedures to the nose\n* patients with greater previous injury or burns to the nasal skin\n* patients with autoimmune skin conditions\n* patients with significant cardiovascular diseases\n* patients unwilling to comply with the study\n* patients who do not want to sign the informed consent, previously approved by the ethics commitee.",true,"ALL","18 Years","80 Years",{"count":19,"type":20},100,"ESTIMATED","OBSERVATIONAL","This is a prospective observation cohort investigation. Patients, that is participants, undergoing primary functional rhinoplasty will be evaluated in terms of measuring capillary blood lactic acid concentration in the nasal skin-soft tissue envelope immediately after the procedure and 7 days after the procedure.\n\nThe aim of our study is to test whether or not different rhinoplasty approaches and volume of the used autologous cartilage grafts impact the nasal skin-soft tissue metabolism.",[24,25,26,27],"Rhinoplasty","Nasal Skin-soft Tissue Envelope Metabolism","Lactic Acid","Autologous Cartilage Grafting",[29,30,31,32,33,34],"Open rhinoplasty approach","Closed rhinoplasty approach","Lactic acid","Skin-soft tissue envelope","Metabolism","Autologous cartilage grafting","NOT_YET_RECRUITING","2024-04-25",{"date":38,"type":39},"2024-04-29","ACTUAL",{"date":41,"type":20},"2025-01-02",{"date":43,"type":20},"2026-09-01",{"name":45,"class":46},"University Hospital Sestre Milosrdnice","OTHER",""]