Bilateral Sensorineural Hearing Loss

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Review clinical trials related to Bilateral Sensorineural Hearing Loss. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Noise Reduction With Hearing Aids

The purpose of this study is to use an optimized version of the SEDA algorithm (SEDA-HA) for hearing aids to evaluate the benefit for listeners with varying degrees of hearing loss in realistic environments and evaluate its impact on speech perception and sound quality. The primary objective is to evaluate performance with and without the SEDA-HA algorithm on speech perception and speech reception tasks. The secondary objective is to evaluate performance of and experience with SEDA-HA integrated into a portable hearing aid prototype in the laboratory and in real-world situations outside the laboratory.

Participants needed: 60
Trial details
Age: 16+Biological sex: AllType: InterventionalSponsor: NYU Langone HealthUpdated: Jul 13, 2026Locations: 1
Eligibility criteria

16 years of age and older [+3]

under 16 years of age [+1]

Status: Recruiting

Neural Prediction to Enhance Language

The language outcome of children receiving cochlear implantation to address bilateral sensorineural hearing loss is more variable than that of typical hearing children. The research is focused upon development of neural predictive models based upon brain imaging to forecast language after cochlear implantation on the individual child level. The long-term goal is improving children's language by using predictive models to enable a custom "predict to prescribe" approach to intervene with more effective behavioral therapy for children at risk to develop poorer language. The investigators previously developed models for short term language outcome of English-learning implanted children. The aims of this study are to 1. Develop models able to predict long term outcome for English- learning and Spanish-learning children; and 2. To evaluate whether English-learning children predicted to achieve lower language based on the investigators' previously constructed models can demonstrate significant gains from Parent Implemented Communication Treatment (PICT). PICT is an intensive parent education program about strategies to improve children's communication.

Participants needed: 700
Trial details
Age: 0-5Biological sex: AllType: InterventionalSponsor: Ann & Robert H Lurie Children's Hospital of ChicagoUpdated: Jul 2, 2026Locations: 1
Eligibility criteria

Age 5 years and under. [+7]

Severe motor and /or cognitive disability that would preclude evaluation of prog... [+11]

Status: Recruiting

Binaural Cue Sensitivity in Children and Adults With Combined Electric and Acoustic Stimulation

There is a rapidly growing population of adult and pediatric cochlear implant (CI) recipients with acoustic hearing preservation in the implanted ear(s) allowing for combined Electric and binaural Acoustic Stimulation (EAS). Despite the rapid technological and surgical advancements that have led to this increased prevalence, there is limited research on EAS outcomes-particularly for pediatric EAS listeners-including the expected trajectory of benefit following EAS fitting and underlying mechanisms driving benefit in EAS users of all ages. Thus, the purpose of this project is to provide a comprehensive description of behavioral and electrophysiologic measures of binaural hearing in adults and children both with normal hearing and EAS users.

Participants needed: 200
Trial details
Age: 5+Biological sex: AllType: ObservationalSponsor: Hearts for HearingUpdated: Jan 21, 2026Locations: 1
Eligibility criteria

Pediatric EAS: aged 5-17; Adult EAS: aged 18+ years [+6]

single-sided deafness (SSD)

Status: Recruiting

Assessing the Effect of Computer-based Auditory Training on Adult Cochlear Implant Speech and Quality-of-life Outcomes

The purpose of this study is to compare the effectiveness of a free computer-based auditory training program, Sound Success (Advanced Bionics, Valencia, CA), with the current standard of care of patient-directed auditory training in improving common measures of speech recognition and cochlear implant (CI) specific quality-of-life in new adult CI recipients in their first year post-activation.

Participants needed: 80
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Mayo ClinicUpdated: Aug 1, 2025Locations: 1
Eligibility criteria

Adult patients with a diagnosis of bilateral moderate-to-profound sensorineural...

Patients undergoing revision implantation, completion bilateral cochlear implant... [+2]