Caries

4

Review clinical trials related to Caries. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Post-Debonding Finishing in Orthodontics

This study investigates clinical approaches to orthodontic debonding and post-debonding finishing, focusing on enamel preservation. An observational epidemiological survey was conducted among dental professionals to assess commonly used techniques, instruments, and complications. Results highlight variability in clinical protocols, with mechanical methods being the most widely adopted. The study emphasizes the importance of minimally invasive strategies to reduce enamel damage and improve patient outcomes.

Participants needed: 100
Trial details
Biological sex: AllType: ObservationalSponsor: University of Roma La SapienzaUpdated: Apr 20, 2026Locations: 1
Eligibility criteria

Professional Background: Must be a dental professional with specific clinical kn... [+1]

Non-Orthodontic Professionals: Dental professionals who do not belong to the cat... [+2]

Status: Not yet recruiting

Construction of a Multidimensional Risk Prediction Model for Severe Early Childhood Caries

This study aims to address the high prevalence and recurrence rate of severe early childhood caries (S-ECC) by breaking away from the traditional single biological factor perspective and introducing the theories of "24-hour activity behavior" and "family psychological stress". By collecting clinical and behavioral data from 1,200 preschool children and their parents, it explores the association pathways between parental burnout, children's executive function, sleep/dietary behaviors and S-ECC, and builds a high-precision risk prediction model to provide evidence-based support for the clinical development of personalized prevention strategies.

Participants needed: 1,200
Trial details
Age: 3-6Biological sex: AllType: ObservationalSponsor: The Children's Hospital of Zhejiang University School of MedicineUpdated: Feb 12, 2026
Eligibility criteria

Age range: 3-6 years old (36 months ≤ months < 72 months); [+2]

Suffering from severe systemic diseases (such as congenital heart disease, blood... [+4]

Status: Recruiting

Intraoral Camera-Assisted Parent Training

The aim of this randomized controlled trial is to test the null hypothesis that parent education using an intraoral camera has no effect on children's oral hygiene levels, parental oral health literacy, or plaque accumulation on first permanent molars compared with standard verbal education. 40 children aged 5-7 and their parents will be randomly assigned to two groups. The intervention group will receive real-time visualization of dental conditions and brushing techniques using an intraoral camera, while the control group will receive standard verbal education using a brushing model. Outcomes include children's plaque and gum health and ICDAS caries scores. Secondary outcomes include Occlusal Plaque Index (OPI) on first molars. Assessments will be conducted at baseline and 1-month follow-up. This study tests whether intraoral camera-assisted education leads to better oral hygiene outcomes in children, improves parents' oral health literacy, and reduces plaque accumulation on the first permanent molars compared to standard verbal education.

Participants needed: 40
Trial details
Age: 5-7Biological sex: AllType: InterventionalSponsor: Aydin Adnan Menderes UniversityUpdated: Jan 9, 2026Locations: 1
Eligibility criteria

Systemically healthy children [+3]

Children with special healthcare needs, intellectual disabilities, or autism spe... [+1]

Status: Recruiting

Clinical Performance and Acceptance of Bioflx Crowns

Treating pediatric patients with early childhood caries can be challenging. For clinicians, managing a young child while ensuring high-quality treatment is difficult. It is essential to have the best equipment and materials available. Today, aesthetics are crucial in managing decayed teeth, with zirconia crowns often preferred for their visual appeal, although they require substantial preparation. The newly developed Bioflx crown, combining stainless steel and zirconia properties, offers an alternative solution.

Participants needed: 62
Trial details
Age: 4-8Biological sex: AllType: InterventionalSponsor: Hams Hamed AbdelrahmanUpdated: Nov 7, 2024Locations: 1
Eligibility criteria

A child with primary molars is indicated for full coverage.

Children with any systemic disease [+3]