[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cavity-dental\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cavity-dental":47},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100642802",false,"NCT07648485","Clinical Performance of CAD\u002FCAM Hard Hybrid Ceramic Inlays Versus Resin Composite Inlays in Vital Molars With Extensive Occluso-Proximal Cavities","Clinical Performance of CAD\u002FCAM Hard Hybrid Ceramic Inlays Versus Resin Composite Inlays in Vital Molars With Extensive Occluso-Proximal Cavities: Two-Year Randomized Clinical Trial","Inclusion Criteria:\n\n* Systematically healthy male or female subjects aged 16 to 50 years.\n* Patients with good oral hygiene.\n* Presence of a single vital molar with coronal destruction due to caries, defined as radiographic evidence of caries involving more than 50% of the total dentin thickness with loss of at least one proximal wall.\n* Cavitary preparation involving loss of at least one proximal walls (mesial and\u002For distal), with intact buccal and lingual walls, and all cavosurface margins located in enamel.\n* Presence of functional opposing teeth in stable occlusion\n\nExclusion Criteria:\n\n* Presence of systemic diseases (e.g., uncontrolled diabetes, immune disorders).\n* Current pregnancy or lactation.\n* Documented allergy to resin-based composites or adhesive systems.\n* Evidence of pulpal necrosis or previous endodontic treatment in the target tooth.\n* Presence of cracks or fractures involving the tooth structure.\n* Active localized or generalized periodontal disease.\n* Evidence of parafunctional habits, including bruxism or clenching.\n* High caries risk.","ALL","16 Years","50 Years",{"count":19,"type":20},50,"ESTIMATED","INTERVENTIONAL",[23],"NA","this study aims to compare the clinical performance of hard hybrid ceramics and composite resin indirect restorations fabricated by CAD\u002FCAM technology for the vital teeth with occluso-proximal cavities. the clinical performance assessed include marginal adaptation primarily and in addition to Color match, marginal discoloration, aesthetic anatomic form, recurrent caries and restoration fracture and post-operative hypersensitivity. the clinical performance will be assessed after the restoration cementation, after 6, 12, 18 and 24 months.",[26,27,28],"Dental Caries","Cavity, Dental","Proximal Dental Caries",[30,31,32,33,34],"indirect restoration","CAD\u002FCAM","clinical performance","inlay","hybrid ceramics","NOT_YET_RECRUITING","2026-06-13",{"date":38,"type":39},"2026-06-16","ACTUAL",{"date":41,"type":20},"2026-08",{"date":43,"type":20},"2028-11",{"name":45,"class":46},"Cairo University","OTHER",""]