[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cbcl\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cbcl":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100475974",false,"NCT05477901","Impacts of Cash Transfers on Child Neurodevelopment (Auxilio Brasil)","Mental Health and Bolsa Familia: A Mechanistically Focused Clinical Trial of a Cash Transfer Intervention on Child Brain, Behavior, and Mental Health","Mother:\n\nInclusion Criteria:\n\n1. Age 23-45 years old\n2. Receiving AB cash transfers\n3. Has at least two or more children ages 7- 10 years old at time of recruitment (up to 4 children per family)\n4. Able to consent\n\nExclusion Criteria:\n\n1\\. Mother and child do not reside in same household\n\nChild:\n\nInclusion Criterion\n\n1. Age 7-10 years old\n2. Intellectual Disability\n\nExclusion Criterion\n\n1. Does not reside in same household as the mother\n2. Major Axis I disorder (e.g., Autism, Schizophrenia, Bipolar)\n3. Severe Disability\n4. MRI contradictions (index child only)","ALL","23 Years","45 Years",{"count":19,"type":20},450,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study examines the impact of Auxilio Brasil (AB), a cash transfer program to mothers of school-age children, on resource-deprived populations in Brazil and its protective effects on child neurodevelopment and mental health. The investigators will conduct a randomized clinical trial (RCT) among those already receiving AB in which 300 families will be randomized in a 1:1 ratio to receive either a high ($40\u002Fmonth) or low ($2\u002Fmonth) supplemental transfer for 2 years. Three hundred children (index child participants; 7-10 years old) will be enrolled across both study arms. Additionally, up to 150 siblings (\"sibling participants;\" 7-10 years old) will be enrolled. Eligible families who decide to participate will sign a study-specific informed consent (mother) and assent (child) form. The UNIFESP team will conduct the respective assessments at baseline, approximately 8- and 16- months, 24-months and approximately 6-months post-RCT.\n\nAim 1: Determine the impact of high vs low cash transfers on children's exposure to adversities (ACEs) and neurodevelopment.\n\nAim 2: Determine the impact of cash transfers on children's inflammatory markers and HPA activity\u002Fcortisol.\n\nExploratory Aim: The investigators will explore (i) whether sex\u002Fgender of the children moderates the pathways in the above mediation model; and (ii) whether cash transfer-related effects persist 6 months post-RCT.",[26,27,28,29],"Inflammation","HPA","CBCL","Family Relations","RECRUITING","2026-04-20",{"date":33,"type":34},"2026-04-23","ACTUAL",{"date":36,"type":34},"2025-05-28",{"date":38,"type":20},"2029-01-31",{"name":40,"class":41},"New York State Psychiatric Institute","OTHER",2,""]